Case report: acute liver failure induced by paracetamol toxicity

Journal Title: One Health & Risk Management - Year 2021, Vol 2, Issue 1

Abstract

Introduction. Paracetamol is the most commonly used drug across Western Europe and North America. There is no such trend of using Paracetamol in the Republic of Moldova, thus overdose cases are extremely rare. The mechanisms leading to overdose episodes might induce hepatotoxicity. Clinical case. This present article reports a case of acute liver failure induced by Paracetamol overdose. A 46-year-old man presented to the Medpark International Hospital. He was administered Paracetamol 1000 mg, approximately every 4 hours for 2 days, and 1000 mg twice a day for another 2 days, after an intense physical exertion, followed by muscle fever with myalgia and low-grade fever (37.4 °C) The reason for asking the medical care were pronounced fatigue, nausea, loss of appetite, night sweats, and frequent urination. Conclusion. Eventually, the case was successfully resolved due to N-acetyl-cysteine, administered according to the established treatment scheme, as well as the adjuvant therapy.

Authors and Affiliations

Eugen TCACIUC, Mariana PODUREAN, Olga SCHIOPU, Aurel BATRINAC, Angela SELIVANOV, Dumitru COLOMAN

Keywords

Related Articles

Antibacterial susceptability of E. coli strains isolated from raw milk

Introduction. The processing of most raw milk products can lead to contamination with unwanted microflora due to poor sanitation and hygienic conditions. The inadequate antibiotic use over the past decades has led to the...

Mesenteric panniculitis: therapeutic aspects in the light of a clinical case

Introduction: Mesenteric panniculitis is a rare medical condition. Its incidence is between 0.16% - 3.4%. The small number of cases of PMN and the ignorance of its causes, pathogenesis and treatment significantly affect...

Current issues related to access and use of information on ex situ conservation of plant genetic resources in the Republic of Moldova

Introduction. The rapid development of information technologies has provided challenges and opportunities for effective documentation of plant genetic resources (PGR). Access to information on PGR is essential for their...

Concerns regarding the effects of the COVID19 pandemic on children health

Introduction. The unexpected situations (lockdown, online school, social distancing) introduced from March 2020 to stop the spread of COVID-19 in most countries worldwide, have affected every citizen. Currently, after mo...

Evaluation of the compliance of people with the containment measures and wearing-mask behaviours in different stages of COVID-19 pandemic: An observational study from Turkey

Introduction. Protection measurements should be paid attention so that the regions affected to a great extent gain time for medical care and medical facilities can cope with increasing intensive care cases. The purpose o...

Download PDF file
  • EP ID EP691210
  • DOI 10.38045/ohrm.2021.1.08
  • Views 195
  • Downloads 0

How To Cite

Eugen TCACIUC, Mariana PODUREAN, Olga SCHIOPU, Aurel BATRINAC, Angela SELIVANOV, Dumitru COLOMAN (2021). Case report: acute liver failure induced by paracetamol toxicity. One Health & Risk Management, 2(1), -. https://europub.co.uk/articles/-A-691210