CASE REPORT OF AN INFANT WITH SEVERE VITAMIN D DEFICIENCY RICKETS MANIFESTED AS HYPOCALCEMIC SEIZURES
Journal Title: INTERNATIONAL JOURNAL OF ADVANCED MEDICINE - Year 2017, Vol 1, Issue 4
Abstract
Introduction: Hypocalcemic seizures are uncommon in the post-neonatal period. We report an infant with hypocalcemic seizures caused by severe deciency of vitamin D. Case Outline: A three-month-old male infant was admitted in our hospital with recurrent generalized afebrile seizures. At the clinical examination, the infant showed characteristic rachitic signs, so that after a blood sample was taken for laboratory testing, the infant was given infusion of 2 ml/kg of 10% of calcium gluconate at a rate of 0.5 ml/min. The treatment resulted in immediate termination of seizures and normalization of the consciousness of the infant. Blood sample analysis showed extremely low levels of free and total calcium (0.31/1.19mmol/l) and 25(OH)D (<3 ng/ml), elevated alkaline phosphatase (900 U/l) and parathyroid hormone (293 pg/ml), and low calcium/creatinine ratio (mg/mg) in a portion of urine (0.03), while the levels of serum phosphorus, pH, total protein, albumin and creatinine were within the reference range. Wrist X-ray showed typical signs of rickets. In order to fully stabilize calcium homeostasis, along with 2,000 IU of vitamin D3 daily and standard cow's milk formula, calcium gluconate (80 mg/kg daily) was given orally over a period of two weeks. The treatment resulted in complete stabilization of the infant's condition and rapid improvement in laboratory, radiological and clinical ndings of rickets. Conclusion: Generalized convulsions in the afebrile infant represent a serious and etiopathogenically very heterogeneous problem. Extremely rare, as in the case of our patient, it may be due to severe hypocalcemia caused by a deciency of vitamin D.
Authors and Affiliations
Dr. Shafath Ahmed
Keywords
Related Articles
- EP ID EP626779
- DOI -
- Views 33
- Downloads 0
STUDY OF CORNEAL ENDOTHELIUM CHANGES FOLLOWING TOPICAL CYCLOSPORINE 0.1% EYE DROPS
AIM: To study the changes of corneal endothelium, central corneal thickness and intraocular pressure following topical cyclosporine 0.1% eye drops. METHOD: A single group observational pre-post clinical study. 60 eyes of...
WEEKLY IRON SUPPLEMENTATION – EFFECTIVE IN IMPROVING HAEMATOLOGICAL PARAMETERS THERE BY REDUCING ANAEMIA AMONG CHILDREN.
Background: Anaemia reduction through weekly Iron supplementation is less studied area. This study was done with an objective to nd out effect of weekly Iron supplementation in improving Haematological parameters among...
EVALUATION OF PULSE PRESSURE AS A MONITORING TOOL IN DENGUE INFECTED PATIENTS
INTRODUCTION: Dengue is one of the most important viral diseases especially in the tropicalregions, with four serotypes that belongs to the genus avivirus of the family Flaviviridae. AIM OF THE STUDY: 1.To evaluate the...
ROLE OF HIGH RESOLUTION ULTRASOUND WITH COLOR DOPPLER FINDINGS IN TUBERCULAR CERVICAL LYMPHADENOPATHY”
Introduction To evaluate the Ultrasound, Color Doppler ndings in enlarged cervical lymph nodes in tuberculosis patient. Materials And Methods We evaluated 48 cases of tubercular cervical lymphadenopathy, referred for US...
EPIDEMIOLOGY OF EMERGENCY PEDIATRIC HOSPITALIZATIONS AT A TERTIARY CARE CENTRE IN NORTH INDIA
Background: Epidemiological data assessment is an important tool for measuring the burden of disease in population. Demographic prole, geographical distribution and outcome of the disease can vary in pediatric emergenci...