Case report on a rare pulmonary bacterial infection by Actinomyces odontolyticus in a T-cell large granular lymphocyte leukemia patient
Journal Title: The Journal of Medical Research - Year 2017, Vol 3, Issue 6
Abstract
T-cell large granular lymphocyte leukemia (T-LGLL), a rare and indolent chronic lymphoproliferative disorder, represents 2% to 3% of chronic lymphoid leukemia cases and affects equally male and female around 60 years. It is characterized by neutropenia that can be severe and lead to opportunistic infections. We report here the case of a 67-year old woman that was followed for T-LGLL, who was diagnosed with lung infection due to Actinomyces odontolyticus, a gram positive bacillus and less commonly recognized pathogen of the Actinomyces group. The diagnosis was based on clinical (dry cough, alteration of general state, dyspnoea), CT-scan and microbiologic features. The treatment consisted of high and intensive dose of beta-lactamine over a 6-month long period combined with once or twice-weekly injections of GCSF. Treatment with cyclophosphamide intended at raising neutrophil count ≥1000/mm3 has been successfully implemented.
Authors and Affiliations
Ngo Sack FF, Ianotto JC, Tempescul A, Couturier MA, Saad H, Berthou C, Eveillard JR
Keywords
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- EP ID EP442715
- DOI 10.31254/jmr.2017.3602
- Views 128
- Downloads 0
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