Catastrophic Anti-phospholipid Syndrome Presenting with Symmetrical Peripheral Gangrene
Journal Title: Journal of Advances in Medical and Pharmaceutical Sciences - Year 2016, Vol 9, Issue 1
Abstract
Introduction: Anti-phospholipid syndrome (APS) is an acquired auto-immune thrombophilia and is very rare in children presenting with skin manifestations. Case Report: A case of 12 years old female who presented to the Emergency with discoloration of arms and legs and later developed gangrene which then auto-amputated. Anti-cardiolipin antibodies were found to be positive and skin biopsy findings were consistent with APS. She was diagnosed with catastrophic anti-phospholipid syndrome. Anti- ds antibodies were found to be negative. Conclusion: Criteria for diagnosing APS in children should be developed as the adult APS diagnostic criteria doesn’t seem to apply on peadiatric patients. Prior studies too apply emphasis on this fact.
Authors and Affiliations
Ujala Zubair, Ahmad Faraz, Zarafshan Zubair
Keywords
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- EP ID EP328462
- DOI 10.9734/JAMPS/2016/26577
- Views 96
- Downloads 0
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