Catastrophic Anti-phospholipid Syndrome Presenting with Symmetrical Peripheral Gangrene
Journal Title: Journal of Advances in Medical and Pharmaceutical Sciences - Year 2016, Vol 9, Issue 1
Abstract
Introduction: Anti-phospholipid syndrome (APS) is an acquired auto-immune thrombophilia and is very rare in children presenting with skin manifestations. Case Report: A case of 12 years old female who presented to the Emergency with discoloration of arms and legs and later developed gangrene which then auto-amputated. Anti-cardiolipin antibodies were found to be positive and skin biopsy findings were consistent with APS. She was diagnosed with catastrophic anti-phospholipid syndrome. Anti- ds antibodies were found to be negative. Conclusion: Criteria for diagnosing APS in children should be developed as the adult APS diagnostic criteria doesn’t seem to apply on peadiatric patients. Prior studies too apply emphasis on this fact.
Authors and Affiliations
Ujala Zubair, Ahmad Faraz, Zarafshan Zubair
Keywords
Related Articles
- EP ID EP328462
- DOI 10.9734/JAMPS/2016/26577
- Views 92
- Downloads 0
Anxiolytic Effect of Aqueous Root Extract of Citrus aurantium in Wistar Albino Rats
Anxiety is a very common mental disorder among neurological disorders. Citrus aurantium decoction has been used to treat anxiety- like behaviour, by traditional medicine practitioners in Nasarawa State, Nigeria. The aim...
Effect of Resveratrol on Some Biochemical Parameters in Lead-intoxicated Male Wistar Rats
Resveratrol is a potent antioxidant, demonstrated to ameliorate adverse effects of heat stress-induced toxicity. Information on the ameliorative effect of resveratrol on heavy metals induced organ toxicity is scanty. The...
Review of Phytochemical, Pharmacological and Toxicological Profile of Stereospermum kunthianum
Aims: The review is directed at the phytochemical, pharmacological and toxicological activities of the medicinal plant Stereospermum kunthianum, Cham, (Bignoniaceae) widely distributed in the Guinean-savannah. Results: A...
Effect of Drug-Drug Interactions by Association Rule Discovery among the Elderly
Objective: With the decline of the bodily function, the elderly increased polypharmacy frequency. The results lead to the danger for duplicate drug and drug interactions (DDIs). This study aims to analyze the effect of D...
Monosodium Glutamate Induced Hepatotoxicity and the Possible Mitigating Effect of Vitamin C and Propolis
Monosodium Glutamate (MSG) has been recognized as a relish additive that adversely affects liver function's parameters. The aim of this study was to assess the effects of MSG on the liver enzyme markers, lipid profile an...