CD4 Count as a Determinant in Clinicalepidemiological Profile of HIV Positive Patients: A Cross-sectional Study

Journal Title: Epidemiology International - Year 2018, Vol 3, Issue 3

Abstract

Introduction: With anti-retroviral drugs mortality from HIV has reduced over the past decade. There is a decline in deaths due to HIV/AIDS evident since mid- 2000’s. Progression of disease to different stages largely depends on the immune status of the individual. A depleting CD4 count correlates with progression of HIV. Hence, this study was carried out with the objective to find the various factors affecting the CD4 count. Materials and Methods: Information was gathered from a total of 1000 patient’s on ART medication attending the ART centre at the district government hospital was collected for a period of one year. Descriptive statistics, one sample t test and ANOVA were used for analysis. Results: 71.4% of the attendees the CD4 count was below 500 cells/mm3 . The mean CD4 was significantly higher in: Females [Mean = 450.72 +/-213.63 (p = 0.001)]. It was also significantly different with respect to adherence, duration of disease, habits and opportunistic infections. Conclusion: CD4 count was influenced by gender, age, duration of disease and treatment and by personal habits like smoking and alcohol. It alone can be taken as a predictor of disease progression.

Authors and Affiliations

Anusha Rashmi,

Keywords

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  • EP ID EP455873
  • DOI 10.24321/2455.7048.201812
  • Views 57
  • Downloads 0

How To Cite

Anusha Rashmi, (2018). CD4 Count as a Determinant in Clinicalepidemiological Profile of HIV Positive Patients: A Cross-sectional Study. Epidemiology International, 3(3), 9-14. https://europub.co.uk/articles/-A-455873