CEA A BIOCHEMICAL MARKER FOR DIAGNOSIS AND PROGNOSIS OF GASTROINTESTINAL CANCER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2016, Vol 3, Issue 13
Abstract
Serum tumor markers (TM) are widely used for diagnosis and monitoring of treatment of cancer. Carcinoembryonic Antigen (CEA) is one of the most widely investigated tumor markers in gastrointestinal (GI) cancers. Estimation of circulating tumor markers is a non- invasive quantitative method. Serum levels of CEA were studied for diagnosis and prognosis of gastrointestinal malignancies. 140 subjects were undertaken out of which 35 normal and remaining 105 were GI cancer patients. Serum levels of CEA were analyzed by Enzyme Linked Immunosorbent Assay (ELISA). Result of serum CEA levels of the GI cancer patients and normal subjects were analyzed statistically. It was observed that there was significant increase in (P <0.01) in CEA levels of oesophagus, stomach and colon cancer patients as compared to normal subjects. The levels of CEA decreased significantly after the surgery but the decrease in levels of CEA was not up to the levels as normal control subjects.
Authors and Affiliations
Prathibha Yadav, Vishnu Datt Bohra
Keywords
Related Articles
- EP ID EP232673
- DOI 10.18410/jebmh/2016/99
- Views 81
- Downloads 0
DIABETIC RETINOPATHY-RISK FACTORS, STAGING & MANAGEMENT
INTRODUCTION The objective of Diabetic retinopathy is to determine the risk factors associated with it, stage of retinopathy diagnosed at presentation, management of it and final visual outcome. The prevention is by stri...
TRENDS AND PREVALENCE OF INFECTIOUS MARKERS AMONG BLOOD DONORS FROM BLOOD BANK OF A TERTIARY CARE HOSPITAL
SUMMARY: Blood transfusion services form an integral part of health care; but simultaneously carries the risk of transmission of transfusion transmissible infections. We conducted a 5yr retrospective cross sectional stud...
PROFILE OF SPINAL TRAUMA IN KASHMIR
Spinal cord injury is a devastating condition that affects all regions of the world. A high incidence of spinal cord injury in younger populations has resulted in enormous financial and physical costs for individual and...
UROLOGICAL ABNORMALITIES IN ANORECTAL MALFORMATION- A SINGLE CENTRE EXPERIENCE
BACKGROUND Association of anorectal malformations (ARM) and urological abnormalities have long since been described in literature. Studies have recommended that all children with ARM should undergo an USG of the urinary...
CARDIOVASCULAR COMPLICATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS: A STUDY IN A TERTIARY CARE HOSPITAL
Systemic Lupus Erythematosus is an autoimmune disorder in which organs and cells undergo damage mediated by tissue-binding auto antibodies and immune complexes1 . Systemic Lupus Erythematosus is a multigenic disease. 1 P...