Central corneal thickness: Correlation with intraocular pressure and disease severity in primary open angle glaucoma
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2016, Vol 2, Issue 4
Abstract
Aim: To evaluate the relation between central corneal thickness (CCT), intraocular pressure (IOP) and vertical cup-disc ratio in Primary open angle glaucoma (POAG) compared to normal and to find out correlation between Central corneal thickness and disease severity in POAG. Materials and Methods: Cross sectional study. Hundred patients on treatment for POAG and hundred age matched subjects were studied. Central corneal thickness was measured using ultrasound pachymeter. Intraocular pressure was measured by applanation tonometry. Statistical analysis was done using SPSS version 18. Results: The mean CCT in glaucoma patients was 528.03±33.37 μm in right eye and 529.69±34. 14 μm in the left eye. The mean value obtained for the control group was 541.46±31.20μm in right eye and 541.25±30.32 in left eye. There was no statistical significance in mean CCT values in males and females. CCT was found to decrease with age in both groups. In glaucoma patients there was a positive correlation of CCT with IOP, and a negative correlation with vertical cup-disc ratio (VCDR). Patients with severe glaucoma had thinner cornea. Conclusion: The average CCT obtained for normal as well as glaucoma patients in our study was lower than the suggested value of 555μm as a risk factor for development of glaucoma by Ocular hypertension study group. Patients with severe glaucoma had thinner cornea. Hence our population maybe at a greater risk of developing glaucoma. In patients with POAG, CCT helps to identify patients with thinner cornea who may be at a higher risk of progression, and require more aggressive control.
Authors and Affiliations
Bindu S, Jyothi P. T, Aswathy. P
Keywords
Related Articles
- EP ID EP241497
- DOI -
- Views 133
- Downloads 0
A four year retrospective & prospective study of ophthalmia neonatorum
Introduction: Ophthalmia neonatorum is one of the most common infections occurring in the first month of life. 1 Neonatal ocular infections have been largely associated with various poor perinatal outcomes. The purpose o...
Prospective clinical study on visual outcome following uveitis
Introduction: Uveitis is one of the most common form of intraocular inflammation causing vision loss either directly or via complications such as cataract, glaucoma, macular edema and others. Aims and objectives: 1. To e...
Inter ocular variability of common glaucoma parameters in patients with primary open angle glaucoma
Aim: To assess the intrasubject variability of CCT,IOP and VCDR in patients with POAG compared to normal. Design: Cross sectional study. Materials and Methods: A total of 100 eyes of patients on treatment for POAG and 10...
Qualitative analysis of refractive errors in school children
PurposeTo study the refractive errors and its implication on the quality of life among the children in the semi urban populationMaterials and Methods This prospective crosssectional study was conducted among the 500 chil...
Prediction of severity of intraoperative haemorrhage during external dacryocystorhinostomy upon body- type (physique) rating - a pioneering study
Background and Objectives: One of the most common complications of external dacryocystorhinostomy (DCR) is haemorrhage. Intraoperative haemorrhage not only hinders the procedures but also delays the operation and unfavou...