Cervical squamous intraepithelial neoplasia grade 1: Recurrence, persistence, and progression in untreated women
Journal Title: Cumhuriyet Medical Journal - Year 2016, Vol 38, Issue 4
Abstract
Objective: Low grade cervical intraepithelial neoplasia (CIN) is a relatively common disorder. The course of disease including recurrence, persistence, and progression in untreated women is not well-known. The aim of the present study was to determine the natural history of CIN 1 during a follow-up period of 3 years. Method: This retrospective study involved data extracted from the medical files of 545 patients diagnosed with CIN 1 between 2009 and 2015 in the obstetrics and gynecology department of a tertiary care center. Initial cervical smear results were compared to those on the follow-up visits at 1st, 2nd and 3rd years. Results: Comparison of initial smear results with follow-up samples yielded significant improvements on 1st, 2nd, and 3rd years (p<0.001 for all). In patients ≤ 44 years of age, improvement in smear results on the 2nd year was more noteworthy than those in patients ˃ 44 years (p=0.011). Conclusions: Results of the present study imply that To conclude, our results demonstrated that low-grade CIN lesions are less likely to display a progressive course. Therefore, prolongation of the screening intervals may be logical for the avoidance of unnecessary visits and procedures, improvement of the quality of life and cost-effectivity.
Authors and Affiliations
Hülya Ayık Aydın, Tayfun Toptaş, Tayup Şimşek
Keywords
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- EP ID EP272120
- DOI 10.7197/223.vi.407665
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