Chagas Disease in Dogs
Journal Title: Journal of Veterinary Healthcare - Year 2017, Vol 1, Issue 2
Abstract
Chagas disease is zoonotic illness or an anthropozoonosis caused by flagellated protozoan parasite Trypanosoma cruzi. This infection presents alarming rates of incidence/prevalence, for this reason, is recognized worldwide as one of the 13 most neglected tropical diseases 1. Numerous studies have demonstrated the existence of domestic dogs infected with T. cruzi across endemic areas ranging from southern United States of America to Argentina 2. The reported prevalence varies widely (1.42-92%), depending on ecoepidemiological and sociocultural factors 3. It is important to emphasize that the natural infection in dogs with T. cruzi occurs in the same way as in humans, that is to say, through active transmission by vectors, contamination by feces infected with the parasite through wounds or the conjunctiva, can also occur by ingestion of infected vectors or tissues of wild animals present in the peridomicile or home 4. The transplacental transmission is also an important mode of transmission in dogs 5. Nevertheless, the main mode of transmission in canine species seems to be the ingestion of infected vectors 6. During the life cycle of T. cruzi the trypomastigotes present in the heces of the triatomines are introduced in the mammalian host by contamination of the insect bite or mucosal membranes. The metacyclic form can penetrate a variety of phagocytic and nonphagocytic nucleated cells. Once inside the cells the parasite becomes in amastigote, which are multiplicative forms that divide into cells. Due to the high parasitic load they produce the lysis of the cells and escapes into the cytoplasm. The amastigotes transform to slender trypomastigotes which can invade adjacent cells, this forms can be ingested by triatomines and they transform into epimastigotes Finally, after migration to the bug's hindgut, the epimastigotes differentiate into infectious metacyclic trypomastigotes, in this way the life cycle of this microorganism is completed 7.
Authors and Affiliations
María Elizabeth Márquez Contreras
Keywords
Related Articles
- EP ID EP393364
- DOI 10.14302/issn.2575-1212.jvhc-17-1817
- Views 153
- Downloads 0
Natural Infection by H1-Like Influenza a Virus in South American Camelids from Argentina: Serological Evidences.
Serum samples from wild and domestic South American Camelids (SAC) from Argentina, collected before (2008), during (2009) and after (2010) the 2009 H1N1 influenza pandemic were tested by hemagglutination-inhibition assay...
Profiling Flight Performance of Young Racing Pigeons (Columba Livia) in Training
Two groups of young pigeons were trained and flight parameters profiled over a flight path of approximately 90 km and a number of measures were developed to analyse their flight performances. An aerodynamic model of avia...
Effect of Oxytetracycline Treatment on Postpartum Reproductive Performance in Dairy Buffalo-Cows with Retained Placenta in Egypt
Retained fetal membrane (RFM) is a crucial calving related disorder that affects economic for the farmer and herd health. Retention of Placenta (ROP) is the condition in which the fetal membranes are not expelled within...
Bisphenol A Down-Regulates The mRNA Expression of Steroidogenic Genes and Induces Histopathological Changes in Testes Of Rats
Bisphenol A (BPA) is an endocrine disruptor with a weak estrogenic effect used in industry as a component of food cans. We aimed to study the toxic effects of BPA on mRNA expression of steroidogenic genes and testicular...
Effect of Digestible Threonine Level of Diet on Productive Performance, Commercial Egg Grading and Egg Quality of 55- to 61-Week-Old Laying Hens
The aim of this study was to establish the digestible threonine (dig. Thr) requirements and the ideal proportion between Thr and Lys for Isa Brown laying hens on productive traits and egg quality characteristics from 55-...