Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma

Journal Title: Türkderm - Deri Hastalıkları ve Frengi Arşivi - Year 2019, Vol 18, Issue 4

Abstract

Leiomyomas are rare, benign and solid tumors of the kidney. Although the developments in radiological imaging methods provide early detection of kidney tumors, it is difficult to differentiate leiomyomas radiologically from other malignant renal tumors. Moreover, the definitive diagnosis of leiomyomas can only be achieved by histopathological and also immunohistochemical evaluation after surgical intervention. Immunohistochemically, positive staining with smooth muscle actin and vimentin, whereas negative staining with cytokeratin, S100, Mart1 and HMB45 are the methods used in the differential diagnosis of leiomyomas. In this case series, after preoperative radiological evaluation, two female and two male patients between 45 and 89 years of age underwent laparoscopic treatment with the diagnosis of a malignant mass in the kidney. We aimed to illustrate the clinical, radiological and histopathological relationship of four adult patients who were managed by laparoscopic approach and diagnosed with renal leiomyoma. Renal leiomyomas should be kept in mind in patients with a renal mass before definitive treatment.

Authors and Affiliations

Mehmet Necmettin Mercimek, Ender Özden, Yarkın Kamil Yakupoğlu

Keywords

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  • EP ID EP665795
  • DOI 10.4274/uob.galenos.2019.1212
  • Views 91
  • Downloads 0

How To Cite

Mehmet Necmettin Mercimek, Ender Özden, Yarkın Kamil Yakupoğlu (2019). Challenges in Differential Diagnosis: A Case Series of Four Adult Patients with Renal Leiomyoma. Türkderm - Deri Hastalıkları ve Frengi Arşivi, 18(4), 158-161. https://europub.co.uk/articles/-A-665795