Changes in clinical condition of the eye and in parameters of cell and humoral immunity in iridocyclitis patients under the influence of anti-viral allokin-alpha
Journal Title: Офтальмологический журнал - Year 2016, Vol 0, Issue 6
Abstract
Introduction. Iridocyclitis, inflammatory eye disease of the uvea, is a topical issue not only in clinical but social regard, considering its high prevalence and disability rates. Purpose. To study changes in the clinical condition of the eye and the state of cellular and humoral immunity in iridocyclitis patients under the influence of allokin-alpha anti-viral drugs. Material and Methods. We observed 41 patients (41 eyes) with acute and chronic iridocyclitis who underwent anti-viral allokin-alpha treatment at Inflammatory Eye Pathology Department at SI “The Filatov Institute of Eye Diseases and Tissue Therapy”. Results. Over the treatment course we observed a significant increase in immunoregulatory index from 1.16% to 2.00%; a relative T-lymphocyte count increased from 38.2±0.5% to 63.4±1.2% and a relative CD-19 lymphocyte count decreased from 24.4% to 21.8%, which reached normal parameters at 18 days after treatment onset. The treatment resulted in VA improvement. Conclusions. Using allokin-alpha anti-viral drug enables to raise treatment success in viral iridocyclitis patients and to improve VA against the background of inflammatory process reduction.
Authors and Affiliations
N. Konovalova, L. Velichko, A. Novik
Keywords
Related Articles
- EP ID EP245475
- DOI -
- Views 121
- Downloads 0
Toxoplasma chorioretinitis in primary myeloperoxidase MPO deficiency: A case report
We present a clinical case of primary partial myeloperoxidase (MPO) deficiency in a young female patient with recurrent episodes of opportunistic infections. Initially, she presented to the clinical immunologist (DVM) se...
Hyperopic astigmatism and strabismus
-
Structure of the chorioretinal complex in the rabbit eye after vitrectomy. Report 3. Vitreous cavity irrigation with 36°С solution
Background: Currently, there are no clear recommendations on temperature modes regarding safety for ocular fundus structures during vitrectomy. Our rabbit study has previously found that formation of numerous vacuoles in...
Proliferative diabetic retinopathy in unsuspected diabetes mellitus: a case report
Introduction. According to World Health Organization, nowadays, the amount of diabetic patients has exceeded 1,000 million people, equaling 3% of the Earth population. Unsuspected diabetes mellitus is a disease in a late...
Removal of Persisting Pupillary Membrane with Refractive Lens Exchange
Background. Clinical characteristics, histological structure, and surgical technique of persisting pupillary membrane (PPM) have been presented in the modern literature in insufficient and, in some cases, contradictory r...