CHANGES IN THE SURFACE OF DYING CELLS AND IM MUNE RESPONSE
Journal Title: Праці Наукового товариства ім. Шевченка - Year 2015, Vol 43, Issue 2
Abstract
Surface o f dying cells is undergoing changes, needed for their effective clearance by phagocytes. Ability o f dying cells to indicate to their microenvironment the necessity o f self-elimination is a key feature of apoptosis and is preventing tissue damage and inflammation, attributable to necrosis. Deficiency o f dying cell engulfment leads to the accumulation o f immunogenic components of dying cells and to the formation of autoantibodies and subsequent development of autoimmune disorders. Current review summarizes latest data regarding changes o f the surface o f dying cells and their influence o f neighboring cells, particularly on cells of immune system. It briefly covers the process of cell death and changes on dying cell surface; processes o f dying cell elimination, including signals for attracting phagocytes ("find me” signals), signals for recognition of apoptotic cells ("eat me” signals), signals for recognition of viable cells ("dont eat me” signals);
Authors and Affiliations
Rostyslav BILYY
Keywords
Related Articles
- EP ID EP203446
- DOI -
- Views 107
- Downloads 0
РІВЕНЬ ФАКТОРА НЕКРОЗУ ПУХЛИНИ АЛЬФА ПРИ ГОСТРОМУ ХОЛЕЦИСТИТІ, ГОСТРОМУ АПЕНДИЦИТІ ТА ЧЕРЕВНОМУ ТУБЕРКУЛЬОЗІ В ЗАЛЕЖНОСТІ ВІД ТИПУ АДАПТАЦІЙНОЇ РЕАКЦІЇ
РІВЕНЬ ФАКТОРА НЕКРОЗУ ПУХЛИНИ АЛЬФА ПРИ ГОСТРОМУ ХОЛЕЦИСТИТІ, ГОСТРОМУ АПЕНДИЦИТІ ТА ЧЕРЕВНОМУ ТУБЕРКУЛЬОЗІ В ЗАЛЕЖНОСТІ ВІД ТИПУ АДАПТАЦІЙНОЇ РЕАКЦІЇ
THE REGULARITIES OF OXIDATION OF N-HYDROXYPHTHALIMIDE WITH POTASSIUM PERMANGANATE IN ACIDIC MEDIUM
The kinetics of oxidation of N-hydroxyphthalimide (NHPI) with potassium permanganate in aqueous solutions by spectrophotometry was investigated. It was shown that N hydroxyphthalimide is active reducing agent that easily...
IVAN FRANKO THEME IN THE COMPOSITIONS OF MYROSLAV SKORYK (DEVOTED TO THE ANNIVERSARY OF I. FRANKO)
We offer you the conversation recording between a Classic of Ukrainian Music, Hero of Ukraine, laureate of T. Shevchenko reward Myroslav Skoryk and the representatives of Lviv medical community. The meeting dedicated to...
MORPHOLOGICAL FEATURES OF HUMAN HEART VALVE APPARATUS AND EXPERIMENTAL ANIMALS IN THE NORMAL AND ON THE CONDITIONS OF THE INFLUENCE OF PATHOGENIC FACTORS
The average life expectancy in modern society is markedly increased, due to the development of experimental and clinical medicine. However, it is proved that over the last 10 years cardiovascular diseases have become the...
Вплив географічних факторів на таксономічне багатство ґрунтової фауни колембол [Impact of geographical factors on the taxonomic richness of soil springtails fauna]
The study tested impact of such geographic factors as area, latitude, longitude, and altitude on the taxonomic richness of the soil fauna of Collembola applying correlation and ordination analyses. As a result, it was fo...