Changes of gastric intramucosal pH in obese patients undergoing laparoscopic and open cholecystectomy
Journal Title: Archives of Medical Science - Year 2007, Vol 3, Issue 3
Abstract
Introduction: Gastric intramucosal pH (pHi) reflects splanchnic perfusion, while pneumoperitoneum may cause disturbances in splanchnic perfusion by increasing intra-abdominal pressure (IAP). Obesity is associated with increased IAP. The aim of this study was to compare the effects of laparoscopic cholecystectomy and open cholecystectomy on pHi in obese patients. Material and methods: Sixty obese patients (BMI 30-40 kg/m2), aged 30-70 years, scheduled for cholecystectomy under standardized general anaesthesia were randomized to receive either laparoscopic cholecystectomy (LC group, n=30) or open cholecystectomy (OC group, n=30). pHi was calculated using gastric air tonometry. Measurements of pHi occurred in four phases: phase I (after induction of anaesthesia but before surgical incision), phase II (15 min of pneumoperitoneum in the LC group or 15 min after surgical incision in the OC group), phase III (end of operation) and phase IV (60 min after patients’ awakening). Results: Intraoperatively, a slight decrease of pHi was observed in both groups without reaching significance. In contrast, at the 1st postoperative hour a statistically significant difference was revealed between the two groups (OC: 7.41±0.038 vs. LC: 7.37±0.05, p
Authors and Affiliations
Paraskevi Matsota, Tatiana Sidiropoulou, Ageliki Pandazi, Chrysanthi Batistaki, Stamo Matiatou, Georgia Kostopanagiotou
Keywords
Related Articles
- EP ID EP102105
- DOI -
- Views 190
- Downloads 0
What is new in medicine What is new in urology?
TGF-β regulates invasive behavior of human pancreatic cancer cells by controlling Smad expression
Introduction: To investigate the role of Smads in tumor cell activation, we examined changes in Smad expression as well as changes in proliferative and invasive behaviors in transforming growth factor-β (TGF-β) – stimula...
From Editor-in-Chief Dear Readers
Glial cell line-derived neurotrophic factor enhances the invasive ability of pancreatic cancer cells by regulating urokinase-type plasminogen activator and matrix metalloproteinase
<br /> The interaction between endothelin-1 and C-reactive protein and their impact on long-term prognosis after percutaneous coronary interventions