Changing Trends in Antibiotic Resistance Profile of Salmonella enteritica species in a Tertiary Care Hospital in Central Kerala
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 10
Abstract
Background: Infections due to salmonella is an important cause of significant morbidity and mortality in many developing countries. Salmonella Typhi being the major causative agent and affects roughly 21.6 million people each year. Objective: A retrospective study was conducted to analyze the antibiotic sensitivity pattern of Salmonella enterica species isolated from clinical specimen from a tertiary care hospital. Materials and Methods: A total of 39 Salmonella enterica species isolated from the blood and stool samples were analyzed from the period of 2011 January to 2017 June. Patients were in the age group of 2-63 years. Salmonella Typhi was the predominant isolate 74% (29). These isolates were tested for antimicrobial susceptibility according to the CLSI guidelines. Results: No Multidrug resistant (MDR) strains were isolated where as sensitivity to Ciprofloxacin and Azithromycin decreased gradually since 2012. Conclusion: Since 1987, when ciprofloxacin was approved for clinical use, fluoroquinolones (FQs) have been widely prescribed for a diverse range of infections, including bacterial enteritis and typhoid fever. A broad antibacterial spectrum, favorable safety profile, and excellent oral absorption have contributed to the popularity of these agents. However, marked increases in FQ resistance were observed within a decade of the introduction of these agents, and Salmonella infections have typified this trend. A careful consideration should be given before deciding the antibiotic for treatment in order to prevent the emergence of antibiotic resistance.
Authors and Affiliations
Dr Reena John
Keywords
Related Articles
- EP ID EP528488
- DOI -
- Views 41
- Downloads 0
A Novel Method of measuring metamorphopsia in macular diseases using computerised D charts
Purpose: This study examines the ability of the computerised D chart to detect and quantify metamorphosis in different macular disorders and compare the results with other clinical measurements such as visual acuity, Ams...
Paratesticular Liposarcoma: A Diagnostic Challenge
Liposarcoma of the spermatic cord is rare. It usually presents as a painless slowly-growing scrotal mass of consistency like lipoma. Inguinal orchiectomy is an adequate surgical approach. Retroperitoneal lymphadenectomy...
Truth Disclosure –Its Influence on the Quality of Life in Cancer Patients at A Tertiary Care Teaching Hospital
Background: The dilemma of whether and how to disclose a diagnosis of cancer or any other terminal illness continues to be a subject of worldwide interest. In many countries around the world, cancer patients are often no...
A Morphological & Topographical Study of Nutrient Foramina in Dry Human Clavicles of Rajasthan State
Introduction: Human beings are bestowed with the power of bipedal locomotion and the clavicle acts as a strut to allow the free movement of the upper limb away from the chest wall.2 The clavicle (collar bone) is an unusu...
An Interdisciplinary Challenge- Growing Interest on Laparoscopic Surgery during Early & Advanced Stage of Pregnancy
A literature search was performed using Medline and the search engine Google. Criteria for selection of literature were methods of analysis (statistical or non statistical), operative procedure (only universally accepted...