Changing Trends of MRSA Isolation in Tertiary Care Hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2017, Vol 3, Issue 3
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial infections worldwide. The aim of study is early detection of MRSA and antibiotic sensitivity pattern. Early detection of MRSA is necessary to implement effective control measures and control their spread in Hospital. Materials and Method: The bacterial isolates from various clinical specimens of patients admitted in our hospital were cultured as per standard protocol and all isolates of Staphylococcus aureus obtained were included in the study. The antimicrobial susceptibility testing was performed by Kirby–Bauer disc diffusion method. The isolates were tested for methicillin resistance by using cefoxitin by disc diffusion method Interpretation of result was done using CLSI 2016 guidelines. Results: During a period of one year, a total of 464 isolates of S. aureus were studied and 186 (40%) were found to be methicillin-resistant. The maximum isolation of MRSA was from pus samples 77 (41%). MRSA isolates showed greater resistance to multiple drugs. 72% of MRSA isolates were resistant to Amoxclav, 61% to Clindamycin, 60% of Penicillin and Co-trimoxazole, 54% to Erythromycin and 41% to Gentamycin. However, all strains were sensitive to Vancomycin. Conclusion: The regular surveillance of MRSA may be helpful in formulating and monitoring the antibiotic policy. Monitoring the epidemiology and the burden of MRSA infections is crucial to control of MRSA and its spread of infection. This may also help in preserving antibiotics like Vancomycin, only for life-threatening Staphylococcal diseases.
Authors and Affiliations
Mangala Suresh Harbade, Anil A. Gaikwad, Jyoti A. Iravane, J. B. Bhakare, A. S. Damle
Keywords
Related Articles
- EP ID EP305651
- DOI 10.18231/2455-6807.2017.0026
- Views 107
- Downloads 0
RF and Anti-CCP Antibody Tests- A comparative study in the Diagnosis of Rheumatoid Arthritis in a Tertiary Care Hospital
Introduction: Rheumatoid arthritis (RA) is autoimmune disease associated with chronic inflammation of joints causing deformities and functional impairment. Diagnosis primarily depends on clinical manifestations because o...
Isolation & study of multidrug resistant Acinetobacter from various clinical samples in a tertiary care hospital
Introduction: Nosocomial infections with Acinetobacter are being increasingly reported worldwide from debilitated& Critical care patients. Multidrug resistance among Acinetobacter are now a major cause of concern. So the...
Evaluation of anticancer activity of Melaleuka Alternifolia. (i. e. tea tree oil) on Breast cancer cell line (MDA MB)- An in-vitro study
Introduction and Aims According to Globocan 2012 India along with United States and China collectively accounts for almost one third of the global breast cancer burden India is facing challenging situation due to 1154 in...
Bacteriological profile and antibiogram of urinary tract infections at a tertiary care hospital
A prospective laboratory based observational study collaborating with medicine, surgery, paediatrics, nephrology, urology, obstetrics & gynaecology and STD departments was carried out over a period of one year with 500 p...
Clinico-Mycological profile of Dermatophytes in Vijayapur, Karnataka
Introduction: Dermatophytosis is common superficial mycoses affecting human beings. Dermatophytes presents with inflammatory response, intense itching and lesion of cosmetic importance. This study aimed at isolation, ide...