Changing Trends of MRSA Isolation in Tertiary Care Hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2017, Vol 3, Issue 3
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial infections worldwide. The aim of study is early detection of MRSA and antibiotic sensitivity pattern. Early detection of MRSA is necessary to implement effective control measures and control their spread in Hospital. Materials and Method: The bacterial isolates from various clinical specimens of patients admitted in our hospital were cultured as per standard protocol and all isolates of Staphylococcus aureus obtained were included in the study. The antimicrobial susceptibility testing was performed by Kirby–Bauer disc diffusion method. The isolates were tested for methicillin resistance by using cefoxitin by disc diffusion method Interpretation of result was done using CLSI 2016 guidelines. Results: During a period of one year, a total of 464 isolates of S. aureus were studied and 186 (40%) were found to be methicillin-resistant. The maximum isolation of MRSA was from pus samples 77 (41%). MRSA isolates showed greater resistance to multiple drugs. 72% of MRSA isolates were resistant to Amoxclav, 61% to Clindamycin, 60% of Penicillin and Co-trimoxazole, 54% to Erythromycin and 41% to Gentamycin. However, all strains were sensitive to Vancomycin. Conclusion: The regular surveillance of MRSA may be helpful in formulating and monitoring the antibiotic policy. Monitoring the epidemiology and the burden of MRSA infections is crucial to control of MRSA and its spread of infection. This may also help in preserving antibiotics like Vancomycin, only for life-threatening Staphylococcal diseases.
Authors and Affiliations
Mangala Suresh Harbade, Anil A. Gaikwad, Jyoti A. Iravane, J. B. Bhakare, A. S. Damle
Keywords
Related Articles
- EP ID EP305651
- DOI 10.18231/2455-6807.2017.0026
- Views 104
- Downloads 0
Enhancement of yield of acid fast bacilli in smear negative sputum microscopy with sodium hypochlorite decontamination sedimentation technique
Introduction: To study usefulness of sodium hypochlorite (bleach) decontamination sedimentation technique to increase yield of acid fast bacilli (AFB) in sputum smear negative clinicoradiologically suspected pulmonary tu...
Prevalence of Nasal carriage of coagulase negative staphylococci and its antimicrobial susceptibility among ICU health care workers at a tertiary care hospital of Barabanki, UP
Introduction Health care workers HCW including medical as well as paramedical workers are a potential source of carrier of infection for the patients admitted in different intensive care units ICU The anterior nares are...
Bacteriological profile in UTI Cases with special reference to Amikacin sensitivity in a tertiary Care centre in Western UP
Introduction UTI is the most common bacterial infection worldwide with adult women being 30 times more likely to suffer from it than men due to short urethra and proximity of uretheral opening with anal canal Escherichia...
Enteric protozoan parasitic infections in HIV seropositive individuals
Background: Parasitic infection of the intestinal tract is a major source of disease in patients with HIV particularly in the tropics where diarrhoea is a common complaint with variable severity and specific pathogens ar...
Antibiotic profile of enterobacter isolates from various clinical samples – A study from a tertiary care hospital
Introduction Enterobacter species especially Enterobacter cloacae are important nosocomial pathogens They cause infections of the lower respiratory tract skin soft tissue urinary tract and occasionally sepsis Enterobacte...