Changing Trends of MRSA Isolation in Tertiary Care Hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2017, Vol 3, Issue 3
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of nosocomial infections worldwide. The aim of study is early detection of MRSA and antibiotic sensitivity pattern. Early detection of MRSA is necessary to implement effective control measures and control their spread in Hospital. Materials and Method: The bacterial isolates from various clinical specimens of patients admitted in our hospital were cultured as per standard protocol and all isolates of Staphylococcus aureus obtained were included in the study. The antimicrobial susceptibility testing was performed by Kirby–Bauer disc diffusion method. The isolates were tested for methicillin resistance by using cefoxitin by disc diffusion method Interpretation of result was done using CLSI 2016 guidelines. Results: During a period of one year, a total of 464 isolates of S. aureus were studied and 186 (40%) were found to be methicillin-resistant. The maximum isolation of MRSA was from pus samples 77 (41%). MRSA isolates showed greater resistance to multiple drugs. 72% of MRSA isolates were resistant to Amoxclav, 61% to Clindamycin, 60% of Penicillin and Co-trimoxazole, 54% to Erythromycin and 41% to Gentamycin. However, all strains were sensitive to Vancomycin. Conclusion: The regular surveillance of MRSA may be helpful in formulating and monitoring the antibiotic policy. Monitoring the epidemiology and the burden of MRSA infections is crucial to control of MRSA and its spread of infection. This may also help in preserving antibiotics like Vancomycin, only for life-threatening Staphylococcal diseases.
Authors and Affiliations
Mangala Suresh Harbade, Anil A. Gaikwad, Jyoti A. Iravane, J. B. Bhakare, A. S. Damle
Keywords
Related Articles
- EP ID EP305651
- DOI 10.18231/2455-6807.2017.0026
- Views 114
- Downloads 0
Bacteriological profile and antibiogram of urinary tract infections at a tertiary care hospital
A prospective laboratory based observational study collaborating with medicine, surgery, paediatrics, nephrology, urology, obstetrics & gynaecology and STD departments was carried out over a period of one year with 500 p...
Locally acquired Visceral Leishmaniasis - First reported case in Northern Province of Sri Lanka
Visceral leishmaniasis is a vector borne protozoan disease, mainly caused by Leishmania donovani and Leishmania infantum. Leishmania donovani is the principal cause in Sri Lanka. This is the first case of locally acquire...
Correlation of hematological parameters in Malaria positive cases – A retrospective study in rural Melmaruvathur, South India
Background: Malarial infection is endemic in many countries of Asia, South Pacific, North Africa, Middle East and South and Central America. It is well known that it affects the haemopoietic physiology and induces change...
Changing trend in clinico-mycological profile of dermatophytosis of skin in Eastern India
Introduction Dermatophytosis is one of the most prevalent cutaneous mycosis and a public health problem in West Bengal as well as in India Its footprint spans far and wide across urban and rural Bengal with a distributio...
Antibiotic profile of enterobacter isolates from various clinical samples – A study from a tertiary care hospital
Introduction Enterobacter species especially Enterobacter cloacae are important nosocomial pathogens They cause infections of the lower respiratory tract skin soft tissue urinary tract and occasionally sepsis Enterobacte...