CHARACTERISTICS AND THERAPEUTIC EFFECTS OF THE NOVEL FREE RADICAL SCAVENGER – EDARAVONE
Journal Title: Nature & Science - Year 2020, Vol 2, Issue 4
Abstract
Edaravone is the first free radical scavenger which approved clinically and has an ability to decrease the level of free radicals in cells. Edaravone is a strong antioxidant, which can protect different cells (e.g. endothelial cells) against damage by ROS by inhibiting the lipoxygenase metabolism of arachidonic acid, by trapping hydroxyl radicals, by increasing prostacyclin production, by inhibiting alloxan-induced lipid peroxidation, etc. Because of that, Edaravone is used in treatment of diseases which are associated with oxidative stress.
Authors and Affiliations
Mirza Mikayil Aliyev, Ulduz Yunis Safarova, Shafiqa Jahangir Jafarova
Keywords
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- EP ID EP759444
- DOI 10.36719/2707-1146/05/17-20
- Views 6
- Downloads 0
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