CHARACTERISTICS OF THE FUNCTIONAL STATE OF THE HYPOTHALAMIC-PITUITARY-OVARIAN SYSTEM IN WOMEN OF REPRODUCTIVE AGE WITH OVARIAN EXHAUSTION SYNDROME
Journal Title: International scientific journal Science and Innovation - Year 2024, Vol 3, Issue 4
Abstract
The issue of estrogen deficiency remains a key area of focus in both scientific research and practical gynecological endocrinology. The negative impact of hypoestrogenism and possible ways of its correction have been thoroughly studied during the menopausal period, yet a significant decrease in the level of sex steroids can be observed at various stages of a woman's life: in juvenile and reproductive periods (Dedov I.I. et al., Ailamazyan E.K., 2007). Literature analysis indicates that ovarian exhaustion syndrome (OES), as a type of ovarian hypofunction, has been increasingly observed in recent years among relatively young individuals, aged 20–40 years (N.V. Barkalina, 2010). There are many conflicting opinions about the nature of this condition: some authors believe that it involves primary ovarian damage (Mal'tseva L.I. 2010), while others think that the primary damage occurs in the central structures of reproductive function (L.B. Butareva, M.A. Shakova, 2010). Finally, there is a viewpoint that excludes simultaneous damage to all structures of the reproductive system (N.A. Zhakhur, L.A. Marchenko, 2010). In this context, the aim of the current study was to investigate the pathogenetic mechanisms underlying menstrual function disorders by analyzing individual fluctuations in the levels of gonadotropins and ovarian steroid hormones and correlating them with the clinical characteristics of the examined patients.
Authors and Affiliations
Tillashaykhova M. Kh.
Keywords
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- EP ID EP735555
- DOI 10.5281/zenodo.11090360
- Views 11
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