CHARACTERIZATION & EVALUATION OF ANTIBACTERIAL, ANTIFUNGAL ACTIVITY OF ENVIRONMENT FRIENDLY CAPPARIS DECIDUA MICROEMULSION
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
Objective: The present study was undertaken with the objective to develop microemulsion from the ethanolic extract of the plant, Capparis decidua and evaluate its potency against microorganisms (bacteria & fungi).Methods: The solubility of the extract was tested in various solvents to determine the oil phase to be used in the microemulsion system. Microemulsion formulations were developed from the plant extract and their physico-chemical studies were carried out as per standard parameter.Results: The prepared microemulsion was tested for its antimicrobial and antifungal activities. Preliminary screening of the microemulsion showed the potent antimicrobial and antifungal activity. The development of microemulsion was confirmed by Transmission Electron Microscopic (TEM) analysis.Conclusion: 5% (w/w) microemulsion from the ethanolic extract of the Capparis decidua was successfully prepared. The microemulsion was found to possess potent antibacterial and antifungal activities.Â
Authors and Affiliations
Sandeep Kumar Dixit, Punita Kumari, Rajmani Prajapati, S. K. Raza, L. K. Thakur
Keywords
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