Characterization of Hepatitis C Virus (HCV) Genotypes with Spectrum of its Viral Load
Journal Title: Scholars Academic Journal of Biosciences - Year 2017, Vol 5, Issue 1
Abstract
The Hepatitis C virus (HCV) is the most common cause of chronic liver disease and is increasing worldwide. Proposed study includes 24 clinical samples, processed for HCV RNA viral load and HCV genotyping. HCV RNA viral load ranges in between 1.00×101 IU/ml to > 1.00×108 IU/ml and the cases with high viral load were further processed for the genotyping. Out of 24 specimens characterized genotype 3a was prevalent in 72.72% (8/24) cases and HCV genotype 1b was in 27.27% (3/24) cases followed by HCV genotype 4a, which was in 27.27% (3/24) cases. In 13 cases target was not detected due to low viral load. 8 cases were for HCV genotype 3a of which 5 were males & 3 females, followed by HCV genotype 1b (3 males) & 4a (3 females). The genotype 3a was found in 8 (72.72%) patients. Genotype 1b was seen in 3 (27.27%) patients. Genotype 4a was seen in 3 (27.27%) patients. Genotype 2a was seen in only 1 (9.09%) patient. From the current study genotype 3a was most prevalent and can be further studied. The outcome of HCV genotyping is of almost clinical value as there are various regimens available to treat different types of HCV genotypes.
Authors and Affiliations
Anchal Chaurasia, Vinita Sangela, Binish Jawed, Mukta Sehgal, Vatsal Prashar, Sachin Kumar, Indu Bushan, Gulshan Kumar Dhingra, Meenakshi Bahuguna, Narotam Sharma
Keywords
Related Articles
- EP ID EP397729
- DOI -
- Views 51
- Downloads 0
Distribution of Marine Crabs from the Marine National Park, Gulf of Kachchh
Crabs are known to flourish in various turbid environments around the world. The Gulf of Kachchh (GOK) is one of the world’s richest Marine National Park (MNP); southern part of GOK has 42 islands which provide shelter f...
Biological Control of Locusts and Grasshoppers Using Some Fungi
Fungal strains such as Metarhizium anisopliae, Beauveriam bassiana, Metarhizium flavoride, and Entomophaga grylli associated with soil were isolated from various insects including termites, and screened for their ability...
Distribution of Fractures on CT Facial Bones in a TertiaryHospital in Chennai
Facial bone fractures and associated soft tissue injury is common in trauma patients and a quick and accurate diagnosis is essential for timely intervention. Based on the population studied the epidemiology of the fractu...
Laterite Soil as Low Cost Arsenic Adsorbent: A case study from Sahibganj District, Jharkhand.
Abstract: The Arsenic contamination of groundwater has recently been reported from Sahibganj, Jharkhand, which is one of the most backward tribal dominated districts of India, causing immense hardships to the poor inhabi...
Bacteriological analysis of plastic and wood chopping boards
Abstract: This study was conducted to compare the microbial load of used plastic and wood chopping board samples and to determine the presence of Salmonella sp. and other Enterobacteriaceae species from the samples. Plat...