Characterization of porcine β-casein G allele(CSN2G)

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Characterization of porcine β-casein G allele(CSN2G)

Journal Title: Animal Biology & Animal Husbandry - International Journal of the Bioflux Society - Year 2011, Vol 3, Issue 2

Abstract

Following the sequencing of porcine (Sus scrofa) β-casein cDNA we have identified a new allele at this locus (CSN2). Our sequence (GenBank accession number GU827390) differs from the sequence reported by Alexander and Beattie (X54974) in the following positions: 294, 443, 468, 647, four SNPs being observed. Because of the guanine in position 294 differentiating the newly found allele from all other previous sequences, we have chosen to name this allele “G”. This is in fact a silent mutation, both the codons CCT and CCG respectively (position 83 in the mature protein) encoding the same amino acid (Pro). Taking in consideration all the differences found at DNA level, the protein derived from the nucleotide sequence of G allele is unique (there are no 100% similarities when compared to all otherknown protein sequences). For future references we propose, for this allele, the nomenclature: CSN2G.

Authors and Affiliations

Mihai Şuteu, Augustin Vlaic, Robert Renaville

Keywords

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EP ID EP124640
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