CHARACTERIZATION OF THE MUCILAGES EXTRACTED FROM HIBISCUS ROSA-SINENSIS LINN AND HIBISCUS MUTABILIS LINN AND THEIR SKIN MOISTURIZING EFFECT
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 11
Abstract
Objective: The present study was aimed to investigate the physicochemical properties, chemical characterization and skin moisturizing effect of the mucilages extracted from Hibiscus rosa-sinensis (HR), and H. mutabilis (HM).Methods: The HR and HM leaves were extracted with distilled water to obtain their mucilages. Then dried and powdered. The physicochemical properties of the mucilage powders, including pH value, swelling index, loss on drying, solubility, total ash, acid-insoluble ash and carbohydrate content were evaluated. The polysaccharides were isolated from the mucilages and purified by DEAE-650M column and identified the sugar unit constituents by acid hydrolysis, followed by TLC and HPAEC analyses. The short-term moisturizing effect of the mucilages was determined on pig skin using Corneometer®.Results: The yield of HR and HM mucilages was 21% and 15% w/w. Each of mucilage showed the specific physicochemical properties. The main component of HR and HM mucilages was acidic polysaccharides named as AHR and AHM. The major components with the Mol% of AHR were 27% galactose, 24% rhamnose, 19% galacturonic acid, and 18% arabinose, while AHM were rich in 27% rhamnose, 25% galactose, 18% xylose, 16% arabinose and 9% galacturonic acid. The skin moisturizing effect of 0.2 % HR mucilage was significantly more effective than 0.2% HM mucilage, 0.2% hyaluronic acid, 5% propylene glycol and 5% butylene glycol at 30 min after application.Conclusion: The results suggest that mucilage extracted from Hibiscus rosa-sinensis was more superior in quality than Hibiscus mutabilis mucilage for using as a good moisturizer in the skin care product.Â
Authors and Affiliations
Waruttaya Kassakul, Werner Praznik, Helmut Viernstein, Darunee Hongwiset, Ampai Phrutivorapongkul, Pimporn Leelapornpisid
Keywords
Related Articles
- EP ID EP579339
- DOI -
- Views 49
- Downloads 0
INFLUENCE OF A BIOLOGICALLY ACTIVE COMPOUND FROM SUBSTITUTED THIADIAZINES ON TRANSAMINASE ACTIVITY IN MYOCARDIAL HOMOGENATE IN EXPERIMENTAL MYOCARDIAL INFARCTION
Objective: Earlier works have reported on the effectiveness of the compounds of the group of substituted 5R1, 6R2, 3,4-thiadiasine-2-amines for treating experimental myocardial infarction, conditioned by the immune-modif...
THE PRELIMINARY PHYTOCHEMICAL ANALYSIS AND ORAL ACUTE TOXICITY STUDY OF STEM BARK OF SYZYGIUM CUMINI
Objective: The current subject field was carried out to evaluate phytochemical analysis and acute toxicity study of the stem bark of Syzygium cumini.Methods: The ethanol extraction was made by the Soxhlet extraction meth...
ASSAY METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS QUANTITATIVE ESTIMATION OF DILOXANIDE FUROATE AND ORNIDAZOLE IN TABLETS BY RP-HPLC
Objective: To develop an accurate, precise and linear Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method for simultaneous quantitative estimation of Diloxanide furoate and Ornidazole in tablets and va...
MOLECULAR MODELLING AND DOCKING STUDIES OF HUMAN ACROSIN BINDING PROTEIN (ACRBP/OY-TES-1)
Objective: We have made an attempt to identify inhibitors that are bound with Acrosin binding protein (ACRBP/OY-TES-1) through In silico molecular docking studies.Methods: Modeling of ACRBP/OY-TES-1 was performed using I...
EVALUATION OF THE PRESENCE OF THE HEAVY METAL NICKEL IN SAMPLES OF TOBACCO SNUFF (NICOTIANA TABACUM) IN NIGERIA
Objective: Tobacco snuffs a finely ground dark brown coloured powder obtained from dried pulverized leaves of tobacco plant Nicotianatabaccum is commonly used among Nigerians. Since the nickel content and its health impl...