Chemical and Biological Approaches for the Synthesis of Silver Nanoparticles; A mini Review
Journal Title: Trends in Pharmaceutical Sciences - Year 2017, Vol 3, Issue 2
Abstract
Since ancient time silver and silver based compound have been used as a powerful antimicrobial agent in medicine. Discovery of antibiotics pushes the silver away from medicine and pharmaceutical sciences. By emerging resistance strains and reducing the efficiency of antibiotics, silver became point of attentions again, but in a novel form of silver nanoparticles (AgNPs). AgNPs are the most effective and powerful novel antimicrobial with ancient roots. Chemical synthesis is one of the first techniques for synthesis of AgNPs. In this technique silver ions reduced to AgNPs by using chemical reducing agents such as sodium borohydride (NaBH4) and sodium citrate (Na3C6H5O7). Later investigations have shown that biological molecules from living organisms such as bacteria, fungi, algae, and plants can also be used as more safe and in some cases sheep reducing agent for biosynthesis of AgNPs.
Authors and Affiliations
Alireza Ebrahiminezhad, Seyedeh-Masoumeh Taghizadeh, Saeed Taghizadeh, Younes Ghasemi
Formulation and evaluation of an Aloe vera -Licorice combination topical gel: a potential choice for wound healing
Wound healing is a natural body response to injury and consists of three steps; Inflammation, proliferation and remodeling. Natural products have always been attractive in pharmacy and drug delivery and have shown higher...
Drug utilization evaluation of meropenem: an important broad-spectrum antibiotic for the treatment of serious bacterial infections in hospitalized patients
Increasing trend in the development of antibiotic resistance is one the major concerns of health care systems throughout the world. Several factors are responsible of the emergence of this problem of which frequent inapp...
Valproic Acid-Induced Hepatotoxicity and the Protective Role of Thiol Reductants
Valproic acid (VPA) is a widely administered drug against epilepsy and several other neurological disorders. On the other hand, liver injury is a deleterious side effect associated with VPA. Oxidative stress seems to pl...
Assessment of intestinal permeability of paclitaxel in the presence of NSAIDs and P-glycoprotein inhibitors
Paclitaxel is a potent anticancer drug with a unique mechanism of action, which is now administered via IV infusion. Due to the presence of cremophor EL in its formulation it may show anaphylactic reactions. So that oral...
Reduced Biofilm Formation in Menaquinone-7 Production Process by Optimizing the Composition of the Cultivation Medium
Nutrient components in the culture medium can affect not only the growth and metabolic activity of bacteria, but also bacterial attachment to solid surfaces. Based on the fact that response surface methodology (RSM) has...