CHEMICAL COMPOSITION AND ANTICANCER ACTIVITY OF DALDINIA CONCENTRICA (XYLARIACEAE)
Journal Title: World Journal of Pharmaceutical Research - Year 2019, Vol 8, Issue 1
Abstract
The mycochemical study of hexanic (EH), ethyl acetate (EE), and ethanolic extracts (EET) of Daldinia concentrica by thin layer chromatography revealed the presence of terpenes, sterols and coumarins. The presence of flavonoids and quinones has been mentioned only in the ethyl acetate and ethanolic extracts. In vitro bioassays performed on the CA 431 cell line, showed the anticancer activity of the extracts with a greater efficiency for the ethanolic extract (IC50 = 0.03 mg / mL), which seems to depend on the coexiting conjugated secondary metabolites detected.
Authors and Affiliations
Boua Benson Boua
Keywords
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