Chemical constituents from the Aerial parts of Rumex hastatus D. Don

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Chemical constituents from the Aerial parts of Rumex hastatus D. Don

Journal Title: Journal of Pharmaceutical and Biological Sciences - Year 2017, Vol 5, Issue 5

Abstract

Rumex hastatus D. Don (Polygonaceae) occurs in Afghanistan, Pakistan, India, Bhutan and western China as a small perennial shrub and is used as an alternative, astringent, carminative, diuretic, laxative, tonic and to treat bloody dysentery, bilious complaints, blood pressure, cough, diarrhoea, dysentery, fevers, jaundice, headache, lung bleeding, piles, neoplasm, rheumatism, skin diseases, wounds and throat pain. Phytochemical investigation of a methanolic extract of the leaves led to isolate seven new chemical constituents characterized as 3′,4′-dihydroxybenzyl oleate (2), β-sitosterol 3-benzyl ether 3′-capriate (4), β-sitosterol 3-benzyl ether 3′-oleate (5), β-sitosterol 3-(3′,4′-dihydroxybenzyl) ether 3′-linoleate (6), β-sitosterol-3β-benzyl 3′-oxy-3′-O-β-D-galactopyranosyl-(6a→1b)-O-β-D-galactopyranosyl-(6b→1c)-O-β-D-galactopyranosyl-(6c→1d)-O-β-D-galactopyranosyl-2d-capriate (β-sitosterol 3-(3′-hydroxybenzyl) 3′-O-β-D-tetragalactoside 2d-capriate, 7), 1-undecanoxy-3-phenol-3-O-β-D-xylopyranosyl-(2a→1b)- O-β-D-xylopyranosyl-(2b→1c)- O-β-D-xylopyranosyl-(2c→1d)- O-β-D-xylopyranosyl-(2d→1e)- O-β-D-xylopyranoside (n-undecanoxyphenol 3-O-β-D-pentaxyloside, 8) and α-L-glucopyranosyl-(2a→1b)-O-α-L-glucopyranosyl-(2b→1c)-O-α-L-glucopyranosyl-(2c→1d)-O-α-L-gluco- pyranosyl -(2d→1e)-O- α-L -glucopyranosyl-(6e→1f)-O- α-L –glucopyranoside (α-L-hexaglucoside, 9) together with the known compounds tridecyl oleate (1) and β-sitosteryl linoleate (3). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.

Authors and Affiliations

Shahnaz Sultana, Mohammed Ali, Showkat Rasool Mir

Keywords

EP ID EP322158
DOI -
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