Chemotherapy Induced Melanonychia: A Case Report

Abstract

Melanonychia during chemotherapy has been reported in many patients following several doses of certain cytotoxic drugs. Though a mild complication, it may cause anxiety for the patient. We report a patient who developed melanonychia after first dose of cyclophosphamide and vincristine. The patient developed transverse black pigmentation of the nail fingers which started proximally and spread distally to involve all fingernails sparing the toenails. The development of melanonychia associated with chemotherapy is not dose or duration of chemotherapy dependent. However, it should be distinguished from serious causes that may require biopsy and medical intervention.

Authors and Affiliations

Foluke Atinuke Fasola, Oladapo Wale Aworanti

Keywords

Related Articles

Successful Treatment with Dapsone for Refractory Immune Thrombocytopenia

In adult with immune thrombocytopenia (ITP), it has been known that steroids have been used as a first-line therapy. The therapy induced remission in more than 60% of patients. Here, we evaluated the results of dapsone f...

Clinical Course of a Case with Sarcomatoid Renal Cell Carcinoma

Introduction: Renal cell carcinoma (RCC) is the most frequently observed malign neoplasm of the kidney. Its sarcomatoid variant (SRCC) is rare but aggressive. Our aim is to present the clinical course of a 51 year-old pa...

Myocardial Infarction in a Young African Male Using Protein Supplements Rich in Branched Chain Amino Acids & Creatine

Aims: Myocardial Infarction is more likely to inflict patients with major cardiovascular risk factors. Sometimes we come across a few patients with myocardial infarction who doesn’t have any of the typical risk factors f...

Congenital Unilateral Chylothorax in a Non-immune Hydropic Newborn with Down Syndrome

Chylothorax is defined as accumulation of lymph within the pleural space. It is the most common cause of pleural effusion causing respiratory distress in the first few days of life. Congenital chylothorax and Down syndro...

Paradoxical Lymphadenopathy after Successful Treatment of Tuberculous Pleuritis

Tuberculous lymphadenopathy can paradoxically increase in size after initial clinical improvement. This paradoxical reaction during tuberculosis treatment is more common among HIV positive than non-HIV patients. However...

Download PDF file
  • EP ID EP327730
  • DOI 10.9734/IJMPCR/2016/28257
  • Views 112
  • Downloads 0

How To Cite

Foluke Atinuke Fasola, Oladapo Wale Aworanti (2016). Chemotherapy Induced Melanonychia: A Case Report. International Journal of Medical and Pharmaceutical Case Reports, 7(5), 1-5. https://europub.co.uk/articles/-A-327730