Chemotherapy-related nephrotoxicity
Journal Title: OncoReview - Year 2012, Vol 2, Issue 1
Abstract
The development of oncology and increasing prevalence of cancer is associated with rapidly growing group of patients treated with chemotherapeutic agents, which, with the benefits of their use, poses a risk of side effects and severe organ damage. Nephrotoxicity is not the only one of them, but what is more important, the degree of kidney injury determines the toxicity of these drugs to other organs. This review focuses on some nephrotoxic side effects of the most frequently used anticancer drugs, their prevention and treatment. Among the medicines discussed are: cisplatin, carboplatin, mitomycin C, cyclophosphamide, ifosfamide, nitrosourea derivatives, methotrexate, gemcitabine, pemetrexed, cetuximab, interferons and anti-angiogenic drugs.
Authors and Affiliations
Joanna Matuszkiewicz-Rowińska, Mariusz Mieczkowski
Keywords
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