Chest Radiographic Patterns of Smear Positive Tuberculosis in Relation to HIV: A Cross-Sectional Study in a Population with a High Burden of HIV and Tuberculosis
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 35
Abstract
Aim: The purpose of this study was to investigate the chest radiographic patterns of smear positive pulmonary tuberculosis patients in relation to HIV co-infection. Study Deign: Cross-sectional descriptive study Place and Duration of the Study: The study was conducted at Gondar University hospital between May 2004–December 2007. Methodology: We studied chest radiographs of 207 (128 HIV negative and 79 HIV positive) consecutive sputum smear positive pulmonary tuberculosis patients according to the standard classification. Mean and percentages/ proportions were used for descriptive analysis. Chi square test was used to measure association. Results: The prevalence of HIV in patients with smear positive pulmonary tuberculosis was 38.2%. The most common chest radiographic patterns were fibronodular (83.1%), cavity (60.4%), lobar consolidation (49.8%), and brochopnemonic consolidation (9.2%). Lymphadenopthy and pleural effusion were more common in HIV co infected patients (p<0.01). Cavities, upper lobe disease and increased mean number of lung lobes involved were more prominent in HIV negative patients (P<0.05). Despite a higher rate of patients with far advanced CXR patterns in HIV negative TBC patients compared to HIV positive (p<0.026), there was no significant difference in the radiographic, sputum smear conversion or clinical response in terms of increased body mass index after 8 weeks of anti TBC treatment between HIV negative and HIV positive patients. Conclusion: Post primary pulmonary tuberculosis was the commonest chest radiographic pattern at presentation in both HIV positive and HIV negative patients, but atypical chest radiographic presentations were associated with co-infection. It was more common for HIV negative tuberculosis patients to have a radiologically far advanced pattern which did not correspond to the clinical and radiological response. This may prompt a need for revision of the current radiological classification.
Authors and Affiliations
Assefa Getachew, Jonna Idh, Samuel G/Sillasie, Thomas Schön
Keywords
Related Articles
- EP ID EP348681
- DOI 10.9734/BJMMR/2014/7308
- Views 96
- Downloads 0
A Missing Correlation between the Number and Type of MEFV Mutations and Severity of Clinical Manifestations in Egyptian Pediatric FMF Patients
Aims: Previous researches identified the gene for Familial Mediterranean Fever (FMF) and found several different gene mutations that cause this inherited rheumatic disease. The aim of this work is to investigate the corr...
Parotid Lymphoepithelial Lesions and Squamous Cell Metaplasia in Sarcoidosis
Parotid sarcoidosis is rare. We report a case in which sarcoidosis was revealed by parotid nodules. The medical history revealed cutaneo-respiratory atopia, the blood group type was O. The ultrasound examination was sugg...
Socioeconomic Profile and Academic Performance of Students on Campus VIII of the State University of Paraíba, Araruna, Brazil, 2013
Aims: The aim of the present study was to analyze the socioeconomic profile and academic performance of students of three courses on Campus VIII of the State University of Paraíba. Study Design: A quantitative, descript...
An Obturation Technique for Closure of Body Wall Defects
Aims: In the vast majority of instances, closure of abdominal wall defects relies on the tensile strength of transposed native tissue and/or prosthetic material. The purpose of this report is to alert clinicians to a dif...
Mild-Tourniquet Induced Ischaemia-reperfusion Injury Results in Changes to Haematological, Haemostatic and Inflammatory Parameters
Background: Ischaemia-reperfusion injury (IRI) is an underlying condition in cardiovascular disease such as arthrosclerosis and stroke, and occurs during surgery that involves the application of a tourniquet. These clini...