Chest Radiographic Patterns of Smear Positive Tuberculosis in Relation to HIV: A Cross-Sectional Study in a Population with a High Burden of HIV and Tuberculosis
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 35
Abstract
Aim: The purpose of this study was to investigate the chest radiographic patterns of smear positive pulmonary tuberculosis patients in relation to HIV co-infection. Study Deign: Cross-sectional descriptive study Place and Duration of the Study: The study was conducted at Gondar University hospital between May 2004–December 2007. Methodology: We studied chest radiographs of 207 (128 HIV negative and 79 HIV positive) consecutive sputum smear positive pulmonary tuberculosis patients according to the standard classification. Mean and percentages/ proportions were used for descriptive analysis. Chi square test was used to measure association. Results: The prevalence of HIV in patients with smear positive pulmonary tuberculosis was 38.2%. The most common chest radiographic patterns were fibronodular (83.1%), cavity (60.4%), lobar consolidation (49.8%), and brochopnemonic consolidation (9.2%). Lymphadenopthy and pleural effusion were more common in HIV co infected patients (p<0.01). Cavities, upper lobe disease and increased mean number of lung lobes involved were more prominent in HIV negative patients (P<0.05). Despite a higher rate of patients with far advanced CXR patterns in HIV negative TBC patients compared to HIV positive (p<0.026), there was no significant difference in the radiographic, sputum smear conversion or clinical response in terms of increased body mass index after 8 weeks of anti TBC treatment between HIV negative and HIV positive patients. Conclusion: Post primary pulmonary tuberculosis was the commonest chest radiographic pattern at presentation in both HIV positive and HIV negative patients, but atypical chest radiographic presentations were associated with co-infection. It was more common for HIV negative tuberculosis patients to have a radiologically far advanced pattern which did not correspond to the clinical and radiological response. This may prompt a need for revision of the current radiological classification.
Authors and Affiliations
Assefa Getachew, Jonna Idh, Samuel G/Sillasie, Thomas Schön
Keywords
Related Articles
- EP ID EP348681
- DOI 10.9734/BJMMR/2014/7308
- Views 82
- Downloads 0
The Use of the Prague Classification System in the Reporting of Barrett’s Surveillance Endoscopies
Aims: The Prague classification for the reporting of Barrett’s oesophagus has been validated in previous studies and is recommended by the British Society of Gastroenterologists (BSG) in their latest guidelines. In this...
Benign Multicystic Omental Mesothelioma in Pregnancy: A Case Report and Review of the Literature
Benign Multicystic Peritoneal Mesothelioma (BMPM) is a very rare condition of unknown pathogenesis, that occurs mainly in women in their reproductive age (5:1 female/male ratio). The pathogenesis of BMPM is unclear and d...
Sulfasalazine Induced DRESS Syndrome: A Review of Case Reports
Introduction: Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) is designated as a lethal adverse drug effect with characteristic sign and symptoms such as skin rashes, fever, leukocytosis with eosinophilia or at...
Patient Satisfaction with Their Esthetic after Receiving Comprehensive Care at a Dental School
Background: Student training through the delivery of comprehensive care is the key mission of any dental school. Comprehensive care consists of complete patient evaluation and treatments in terms of, the patient’s dental...
Prevalence of Syphilis among Pregnant Women in Two Health Care Facilities in South Western Nigeria
Aims: The prevalence of syphilis has been reported to be on the increase worldwide as a result of the HIV/AIDS pandemic. Maternal syphilis puts the fetus at risk of congenital syphilis with the attendant health risks inc...