Chikungunya vaccine 2014 – A current view
Journal Title: International Journal of Novel Trends in Pharmaceutical Sciences - Year 2015, Vol 5, Issue 5
Abstract
A virus is a small parasite that cannot reproduce by itself. Once it infects a susceptible cell, however a virus can direct the cell machinery to produce more viruses. The most common type of viral disease is the common cold, which is caused by a viral infection of the upper respiratory tract (nose and throat). Chikungunya disease is mostly confined to people living in tropical Africa and Asia and is characterized by a sudden and severe fever, skin rash and joint and muscle pain. Infection with the virus, spread by two mosquito species, typically is not fatal but can cause debilitating symptoms including fever, headache and severe joint pain lasting weeks or months. There is no current treatment and no licensed vaccine to prevent it. Scientists at the National Institute of Allergy and Infectious Diseases, Texas branch of Purdue University have developed a working vaccine for Chikungunya. Several vaccine candidates have reached the stage of human clinical trials. The progress achieved so far suggests that the development of a safe and effective CHIK vaccine is within reach.
Authors and Affiliations
A. Narasimhulu , M. Shankar , T. Shanker Reddy , M. Niranjan Babu
Keywords
Related Articles
- EP ID EP96416
- DOI -
- Views 93
- Downloads 0
Isolation of Methionine - Producing Streptomyces Species from South Indian soil
Actinomycetes isolated from soil were investigated for methionine production, and an isolate, designated SP-05, was recovered. Taxonomic studies showed that the strain has good growth, sporulation and black pigment...
Formulation of pulsatile drug delivery containing anti-asthmatic drug dosage form
The aim of the present research work was to develop Theophylline pulsatile tablet for the acute asthmatic attack. In the present study Theophylline Pulsatile tablet consisting of fast-swelling core tablet coated with a...
Identification of the potential drug candidate for mutational gene IL12B (Asthma – Human) using cheminformatics software and tools.
Asthma (from the Greek άσθμα, ásthma, "panting") is the common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction, and bronchospasm. Symptoms incl...
In-silico construction of phylogenetic tree to establish the relationship amongst family Zingiberaceae found in Manipur, North-east India, based on chloroplast matK gene
Plants belonging to family Zingiberaceae play an important role in terms of both socio-economic and culture of Manipur. A potential barcoding gene, matK could be used to establish the evolutionary relationship and constr...
Identification of Molecular sequence relationships between Culex quinquefasciatus and Aedes aegypti using Bioinformatics techniques
When two symbolic representations of DNA or protein sequences are arranged next to one another so that their most similar elements are juxtaposed they are said to be aligned. Many bioinformatics tasks depend upon success...