Childhood Intracranial Germinoma with Granulomatous Reaction
Journal Title: Turkish Journal of Pathology - Year 2011, Vol 27, Issue 1
Abstract
Central nervous system tumors are the second most common type of childhood cancer in Turkey. Germinomas constitute two thirds of intracranial germ cell tumors. The granulomatous inflammation occurring around germinomas can cause histological diagnostic difficulty. We present a 12-year-old girl with a diagnosis of germinoma in the corpus callosum associated with granulomatous reaction to emphasize the diagnostic challenge which may occur during stereotactic biopsy interpretation or intraoperative consultation.
Authors and Affiliations
Gülen GÜL NİFLİOĞLU, Mehtat ÜNLÜ, Nurullah YÜCEER, Erdener ÖZER
Importance of Thioflavin T in Diagnosis of Renal Amyloidosis <br />
Objective: Amyloidosis represents a group of diseases with deposition of amyloid fibrils. Clinical and histopathological features of renal amyloidosis vary according to the type of precursor protein. Histopathological di...
Lipofibromatous Hamartoma of the Median Nerve in Association with or without Macrodactyly
Lipofibromatous hamartoma is a rare tumour-like condition involving the peripheral nerves, particularly the median nerve. It commonly affects the volar aspect of the hands, wrists and forearms of young adults. Most patie...
Evaluation of p53 and Ki67 Expression Profiles in Basal Cell Carcinomas in a Usual and an Unusual Location
Objective: Owing to their importance in cell proliferation in cutaneous malignancies, we aimed to immunohistochemically compare the expression profiles of p53 and Ki67 in basal cell carcinoma (BCC) cases in both a usual...
Improving Histopathology Laboratory Productivity: Process Consultancy and A3 Problem Solving
Objective: The ISO 17020 quality program has been run in our pathology laboratory for four years to establish an action plan for correction and prevention of identified errors. In this study, we aimed to evaluate the err...
Acute Myeloid Leukaemia with Gene Mutation: A Correlation with Haematological and Immunophenotypic Characteristics and Our Experience in a Tertiary Care Cancer Center in South India
Objective: Molecular genetic analysis of FLT3, NPM1, and CEBPA is already the standard of care in patients with acute myeloid leukaemia (AML) and represents the most frequent genetic alterations and important diagnostic...