Chloroquine Induced Stevens Johnson Syndrome: A Case Report
Journal Title: Scholars Journal of Medical Case Reports - Year 2014, Vol 2, Issue 3
Abstract
The appraised incidence of the Stevens-Johnson syndrome ranges between 1.2 and 6 per million populations per year but the mortality rate is 15%. A 14 year old boy from rural area of Kadapa was admitted in the general medicine department with complaints of skin lesions all over the body with involvement of oral lesions since 10 days. He had a history of fever (high grade and not associated with chills) for the past 10 days and was administered inj. Lariago (Chloroquine-64.5 mg/ml) followed by oral chloroquine (Tablets Lariago, Chloroquine phosphate 250 mg, 2 tables stat, 1 tablet after 6 h, 1 O.D. for 1 day) for empirical treatment of malaria by a local physician. After 24 hours, he developed red patches over the abdomen and extremities associated with burning sensation and itching, which was progressed to all over the body. This adverse reaction is dose-related and can be labeled as Type A class of adverse effect. It can be considered as definite, Probable / conditional adverse drug reaction as per causality assessment of suspected adverse drug reactions. Thus, the hint of this written report is to create awareness about the rare but potentially fatal drug reaction like Stevens-Johnson syndrome with chloroquine which is ordinarily used for endemic malaria in India. Keywords: Adverse drug reaction, Chloroquine, Malaria, Stevens Johnson syndrome
Authors and Affiliations
S Parveen, L Reddenna ,, S Chandra Babu, K Narotham Reddy, R Rajani, E Sam Jeeva Kumar
Keywords
Related Articles
- EP ID EP377034
- DOI -
- Views 69
- Downloads 0
Unusual Fusion Of Premolar And Molar : Case Report
Abstract: Odontogenic anomalies of teeth can be encountered frequently in dental practice. Fusion is the union of two normally separated tooth germs resulting in the formation of a single large tooth. The prevalence of t...
Longitudinal changes in retinal crystals in a patient with Bietti crystalline dystrophy
Abstract: We present a long-term follow-up of a patient with Bietti crystalline dystrophy. The clinical findings were documented over a period of 4 years. The most striking features were crystalline deposits in the retin...
A case of Meningiomylocele Diagnosed by Magnatic Resonance Imaging (MRI)
2years old male baby has a swelling in the posterior lower cervical region discovered by his mother, this swelling increase in size with age. MRI was requested, showed that there is protrusion of the spinal cord and meni...
Mucinous carcinoma of the breast with neuroendocrine differentiation- a rare case report
Abstract: Mucinous carcinoma of breast is one of the rarer forms of breast neoplasms which usually presents as a lobulated, well circumscribed mass with very low incidence of lymph node metastasis. It accounts for 1 -7%...
A Case Report of Tuberculosis of Rectum Mimicking Malignancy
Gastrointestinal tract tuberculosis is uncommon. Anorectal tuberculosis is rare and can mimic malignancy. We present a case of 55-year-old female patient who came to the hospital with complaints of severe epigastric pain...