Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.
Journal Title: Singapore Medical Journal - Year 2011, Vol 52, Issue 3
Abstract
Ketamine is a dissociative anaesthetic agent that is still widely used in veterinary and human medicine. It is increasingly being used as a recreational hallucinogenic drug. Chronic ketamine abuse is known to account for lower urinary tract symptoms and urinary bladder dysfunction. There is now emerging evidence that ketamine misuse is also associated with abnormal liver function tests and biliary tract abnormality. We report three cases of chronic ketamine misuse in three young men who all presented with obstructive jaundice and biliary tract abnormality. We also describe the clinical features, radiological findings and potential underlying mechanisms for this new entity.
Authors and Affiliations
R S C Lo, R Krishnamoorthy, J G Freeman, A S Austin
Keywords
Related Articles
- EP ID EP92049
- DOI -
- Views 124
- Downloads 0
Electrocardiography series. ECG delta waves in patients with palpitation.
It is important to recognise Wolff-Parkinson-White (WPW) syndrome in electrocardiograms (ECG), as it may mimic ischaemic heart disease, ventricular hypertrophy and bundle branch block. In addition, ECG can aid in the loc...
Blood glucose screening in healthy neonates.
A comparison of genotype and markers of disease severity of chronic hepatitis C in patients with and without end-stage renal disease.
Introduction: This study was conducted to compare the genotype and markers of disease severity of chronic hepatitis C (CHC), namely viral load, alanine transaminase (ALT) levels and histopathological findings on liver bi...
Fibrovascular polyp of the oropharynx.
Fibrovascular polyps are benign but rare tumours of the upper digestive tract. In most of the cases reported to date, fibrovascular polyps have originated from the oesophagus or hypopharynx. In 85-90 percent of these rep...
Ministry of health clinical practice guidelines: screening of cardiovascular disease and risk factors.
The Ministry of Health (MOH) publishes clinical practice guidelines on Screening of Cardiovascular Disease and Risk Factors to provide doctors and patients in Singapore with evidence-based guidance on the screening of ca...