Cholestasis as the initial presentation of relapsing polychondritis
Journal Title: Annals of Hepatology - Year 2011, Vol 10, Issue 4
Abstract
Relapsing polychondritis is an immune-mediated disease associated with inflammation in cartilaginous structures and other tissues throughout the body, particularly the ears, nose, eyes, joints, and respiratory tract. Although association with other conditions is seen in about one-third of the cases, liver involvement is not usually observed in those patients. We described a case of liver involvement in relapsing polychondritis, presenting with a predominantly cholestatic pattern. Other conditions associated with abnormal liver tests were excluded and the patient showed a prompt response to steroid therapy. We discuss the spectrum of the liver involvement in relapsing and review the literature.
Authors and Affiliations
Maria da Graça Ferronato, Leonardo Staub, Renata Teixeira Pinto Viana, Lígia da Rosa, Janaína Narciso-Schiavon, Esther Dantas-Correa
Keywords
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