Choroid changes in vortex vein-occluded monkeys
Journal Title: International Journal of Ophthalmology - Year 2018, Vol 11, Issue 10
Abstract
"AIM: To determine acute and chronic choroidal vascular changes after vortex vein occlusion in monkeys. METHODS: One or two temporal vortex veins were occluded in 8 cynomolgus monkeys. Fluorescein angiography (FA), indocyanine green angiogram (ICGA), and enhanced-depth imaging optical coherence tomography (EDI-OCT) were performed preoperatively and at 1d, 1, 4, 8 and 12wk after occlusion. EDI-OCT images were binarized to calculate the choroid vascular index (CVI). RESULTS: ICGA showed delayed filling of choroidal arteries in occluded quadrants in eyes with two occluded temporal vortex veins within 1wk. The thickness of the superotemporal choroid increased 1d and 4wk after occlusion, the thickness of the superonasal and inferonasal choroid increased 12wk after occlusion, and the CVI of the superonasal quadrant increased 8wk after occlusion in eyes with 2 occluded vortex veins. CONCLUSION: Occlusion of two vortex veins leads to hemodynamic and structural changes in choroidal layers in the acute phase, while autoregulation may play the main role in the long term. Occlusion of one vortex vein has little influence on the hemodynamic and structural status of the choroid."
Authors and Affiliations
You-Xin Chen
Keywords
Related Articles
- EP ID EP477343
- DOI 10.18240/ijo.2018.10.03
- Views 50
- Downloads 0
Repeatability of Ophtha Top topography and comparison with IOL-Master and LenstarLS900 in cataract patients
"AIM: To determine the repeatability of Ophtha Top topography and assess the consistency with intraocular lens (IOL)-Master and LenstarLS900 (Lenstar) in measuring corneal parameters among cataract patients. METHODS: Tot...
Change in foveal position based on age and axial length in high myopic eyes
"AIM: To evaluate the influence of age and axial length (AL) on the position of the fovea in patients with high myopia (HM). METHODS: In this prospective study, 96 patients (186 eyes) with HM were consecutively recruited...
Clinical outcomes of a new diffractive multifocal intraocular lens
"AIM: To evaluate clinical outcomes after implantation of a new diffractive aspheric multifocal intraocular lens (IOL) with +3.00 addition power. METHODS: This is a retrospective, consecutive case series of cataract pati...
Early expression of PTX3 in Aspergillus fumigatus infected rat cornea
"AIM: To investigate the expression of pentraxin 3 (PTX3) in rat corneal epithelium at the early stage of Aspergillus fumigatus (A. fumigatus) infection. METHODS: A total of 50 Wistar rats were randomly divided into cont...
Comparison of the inhibitory effect of different doses of subconjunctival bevacizumab application in an experimental model of corneal neovascularization
"AIM: To evaluate the inhibitory effect of subconjunctival bevacizumab as single- and multiple-dose application, and compare their effects on corneal neovascularization in a rat model. METHODS: Thirty adult Sprague-Dawle...