CHROMOSOMAL ABERRATIONS IN MEN IN THE MARRIED COUPLES WITH THE COMPROMISED REPRODUCTION FNCTION
Journal Title: Вісник Одеського національного університету. Біологія - Year 2014, Vol 19, Issue 1
Abstract
Nearly 10-15% of married couples suffer from infertility. Cytogenetic analysis makes it possible to diagnose chromosomal aetiology of infertility and to select respective system of treatment. The aim of the work was to determine karyotype of couples with reproductive problems. Preparations of GTG-differentially stained metaphase chromosomes, prepared in accordance with the standard method, were analysed. In all analysed infertile married couples chromosomal aberrations were identified only in males. Among the identified disorders were: Klinefelter syndrome, Robertsonian translocations between acrocentric chromosomes – 14, 15 and 13, 21, balanced translocations between 16 and 18 chromosomes, pericentric inversions of 8, 9 and 10 chromosomes, de la Chapelle syndrome (46, XX), Y chromosome long arm macrodeletion, fragile chromosomes and presence of enlarged pericentromeric heterochromatin of 16 chromosome. The identified abnormalities resulted in spermatogenesis impairment or non-developing pregnancy in a healthy wife. The performed karyotyping makes it possible to select the optimal tactics for the management of the couple to give birth to a healthy baby
Authors and Affiliations
O. B. Polodienko
Keywords
Related Articles
- EP ID EP395890
- DOI -
- Views 86
- Downloads 0
PHYSIOLOGICAL ACTIVITY OF SHIZOPHYLLUM COMMUNE FR.: FR. AND TRAMETES VERSICOLOR (L.: FR.) QUEL. CULTIVATED ON BREADCRUMB IN SUBMERGED CULTURE
Shizophyllum commune and Trametes versicolor are well-known medicinal fungi which belonged to phylum Basidiomycota and possess immunomodulating, antimicrobial and anticancer activity. The aim of current study was to inve...
DYNAMICS OF THE CONTAMINATIONS WITH FEATHER MITES (ACARI: ASTIGMATA) OF BLACKCAP AND ROBIN MIGRATING THROUGH ZMIINYI ISLAND (THE BLACK SEA, UKRAINE).
Problem. The contamination of the plumage of the Blackcap Sylvia atricapilla (Sylviidae) and the Robin Erithacus rubecula (Muscicapidae), migrating through Zmiinyi island (the Black Sea, Ukraine) with feather mites with...
PHYSIOLOGICAL INDICATORS AND YIELD OF GRAPE VARIETIES AROMATNIY AND CABERNET SAUVIGNON TREATED WITH DRUG AGROMAR
Introduction. Drug AgroMar based on Trichoderma lignorum H. is an ecologically safe biofungicide whose effectiveness in cultivating technical varieties of grapes has not been sufficiently studied under conditions of the...
CHARACTERISTICS OF THE INITIAL STAGE OF VEGETATION DEMUTATION IN FALLOWS UNDER THE DONETSK REGION
The article considers the changes in species composition of herbage and projective cover in the areas taken out of agricultural use of various ages. The ecological certification (by the method of L. Belgard), makes it po...
INFLUENCE OF GSM 900 MHZ RADIATION ON EMBRYO DEVELOPMENT OF JAPANESE QUAIL
Aim: Long-term exposure of humans to low intensity radiofrequency electromagnetic radiation (RF-EMR) leads to a statistically significant increase in tumor incidence. Mechanisms of such effects are unclear, but features...