Chronic Hepatitis C Treatment with New Antiviral Agents
Journal Title: Mediterranean Journal of Infection, Microbes and Antimicrobials - Year 2018, Vol 7, Issue 1
Abstract
Recent advances in our knowledge of hepatitis C virus (HCV) molecular biology have enabled improvements in the efficacy and tolerability of HCV treatment, and in this regard many direct-acting antiviral (DAA) agents have been developed. These drugs target specific stages in the HCV life cycle. Phase 3 clinical trials have demonstrated treatment success rates of 90% with these drugs and their combinations, while real world data indicate a rate of 80-90%. In this review, the use of DAA drugs in the treatment of chronic HCV infection is reviewed in detail.
Authors and Affiliations
Özlem KANDEMİR
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