Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids: Case report and review of the literature
Journal Title: Journal of Neurology and Therapeutics - Year 2016, Vol 2, Issue 2
Abstract
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a brainstem-predominant encephalomyelitis first described by Pittock and colleagues in 2010. CLIPPERS presents with cranial nerve symptoms as well as some cognitive and spinal features. CLIPPERS is a diagnosis of exclusion. Characteristic radiographic and histopathologic findings along with clinical response to steroid suggest the diagnosis. Awareness of the features of CLIPPERS may aid in its prompt recognition, early initiation of treatment, and reduction in its associated morbidity and mortality. We present a case of CLIPPERS in a 48-year-old male patient with initial response to steroid therapy, subsequent relapse, and eventual recovery after therapy augmented with disease-modifying agents.
Authors and Affiliations
Hashwani A, Edwards ML, Raisanen J, Fang X
Keywords
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- EP ID EP562900
- DOI 10.14312/2397-1304.2016-2
- Views 48
- Downloads 0
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