Chronomorphological and pressure changes in a sign of aging - pseudoexfoliation of the eye
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 5
Abstract
Background: Pseudoexfoliation (PXE) is an age-related disorder, a risk factor for glaucoma. The aim of this research was to study the chronomorphological and pressure changes in PXE of the eye. Aims and Objectives: To determine and to compare the anterior chamber depth (ACD), lens thickness (LT), axial length (AL), corneal curvature (CC), and intraocular pressure (IOP) in cases with PXE and in controls. Thence, predict the future onset of pseudoexfoliative glaucoma. Material and Methods: This was a case–control study, patients diagnosed to have PXE with the help of slit lamp, above 50 years were taken as cases and age-matched subjects as controls. Measurement of ACD, LT, and AL by A-scan; CC by Keratometer; and IOP by Schiotz tonometer of both cases and controls were performed. Results: Fourteen cases and seventeen controls were studied. A significant difference in mean IOP (P = 0.029) and AL (P = 0.001) between cases and controls was found. Conclusion: IOP and AL were significantly more in PXE as compared to controls. A significant increase in IOP and AL together may predict the future onset of PXE and hence, may help in early diagnosis of glaucoma and which may be missed in cases of PXE.
Authors and Affiliations
Shailaja S Patil, Anita Herur, Brid S V, Rashmi Neginhal
Keywords
Related Articles
- EP ID EP489399
- DOI 10.5455/njppp.2018.8.1246413122017
- Views 57
- Downloads 0
Effect of prescription waiting time on patient satisfaction mediated by service quality of pharmacy unit in public hospital in Bandung city
Background: The Indonesia National Health Insurance (NHI) is one of the social protections to ensure all people to health. Improving the quality of good service is a demand for pharmacy unit to improve the services quali...
Study of interpeak latencies of waveforms of brainstem auditory evoked potentials in normal healthy persons
Background: Auditory evoked potentials (AEPs) are very small electrical voltage potentials signal generated by a sound through the auditory pathway. Age and gender influence on the brainstem AEPs (BAEPs) deserve keen app...
Gender differences in internet preferences and usage pattern among medical students
Background: Internet began with the development of electronic computers in the 1950s. Internet use is spreading rapidly into daily life, and directly affecting people’s ideas and behavior. With the development of the int...
Leucovorin-induced hypersensitivity reaction in acute lymphoblastic leukemia - A case report
Leucovorin (LCV) acts as an essential coenzyme for nucleic acid synthesis and also it is an active metabolite of folic acid. LCV can be used to selectively “rescue” cells from the adverse effects of methotrexate (MTX). H...
Auditory and visual reaction times during the menstrual cycle
Background: Menstrual cycle is due to cyclic variations in the levels of various sex hormones. The effects of these hormones are not limited to the reproductive system alone but affect other systems including the nervous...