Cinnamic acid and lanostenoic acid derivatives from the leaves of Pyracantha crenulata (D. Don) M. Roem
Journal Title: Journal of Pharmaceutical and Biological Sciences - Year 2017, Vol 5, Issue 3
Abstract
Pyracantha crenulata (D. Don) M. Roem. (Rosaceae) is distributed in the northern Himalayas and China as a perennial shrub. The leaves are used to prepare herbal teas, sun burn creams and facial creams and taken as a nervine tonic. An air-dried leaf powder of P. crenulata was exhaustively extracted with methanol. The concentrated leaf extract was adsorbed on silica gel (60-120 mesh) for the preparation of a slurry. The dried slurry was chromatographed over silica gel column packed in petroleum ether. The column was eluted with petroleum ether, chloroform and methanol successively in order of increasing polarity to isolate β-sitosterol, cis-3,4-dioxyethylene-5-methoxycinnamic acid and lanost-54-en-2β,3β-diol 26-oic acid (cranulanostenoic acid). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.
Authors and Affiliations
Shahnaz SultanaV, Mohammed Ali, Showkat Rasool Mir
Keywords
Related Articles
- EP ID EP321425
- DOI -
- Views 113
- Downloads 0
A prespective review on a novel plant balanites aegyptiaca (linn.)
Since ancient time plants and herbs are used to treat various types of diseases. At that time they were given by Vaidhya and Hakim’s and named as Ayurvedic medicine. Some plants contain many phytochemical constituents wh...
Modulations in haematological aspects of wistar rats exposed to sublethal doses of fipronil under subchronic duration
Fipronil (FPN) a phenylpyrazole insecticide is one of the preferred agricultural chemical known for controlling insect pests. Assessment of its safe and toxic levels has become a matter of serious concern as it is occupa...
Fascinating approach for using metabolites products of living microorganisms as reducing agents for preparing silver nanoparticles
A crucial area of research in nanotechnology is the formation of environmentally benign nanoparticles Both unicellular and multicellular play an important role in synthesis nanoparticles through the production of inorgan...
Isolation, identification, enumeration and antibiotic profiling of microbes from soil contaminated with hospital waste dumbing
Hospital waste is a potential health hazards to the health care workers and public acquired infection, transfusion transmitted diseases. Increasing land and water pollution lead to increasing possibility of contracting m...
Formulation development and invitro evaluation of fentanyl patches for transdermal drug delivery system
Oral drug delivery system has various drawbacks like poor bioavailability due to hepatic metabolism (first pass) and the tendency to produce rapid blood level spikes (both high and low), leading to a need for high and fr...