Cisplatin Induced SIADH in Patients Receiving Concurrent Chemoradiation Therapy: A Rare Clinical Observation
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 11
Abstract
ABSTRACT The Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) can be attributed to various causes such as CNS disorders like head trauma, stroke, pulmonary lesions like TB, bacterial pneumonia, as paraneoplastic syndromes in malignancies, drugs like antidepressants, antineoplastics like cyclophosphamide, vincristine, vinblastine, bortezomib, carboplatin and others. Cisplatin induced SIADH is very uncommon and hence, scarcely reported in literature. Here, we report two cases of dilutional hyponatremia secondary to SIADH that developed in two patients receiving radiotherapy with concomitant cisplatin.
Authors and Affiliations
Chevireddy Praneetha, Bala Venkat Subramanian, Govindu Vaishnavi Deepthi, Pettikota Masthan Basha, Pranabandhu Das
Keywords
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- EP ID EP526288
- DOI 10.7860/JCDR/2018/37939.12220
- Views 62
- Downloads 0
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