CLIMAX IN PREVALENCE OF IRON DEFICIENCY ANAEMIA AMONG PREGNANT WOMEN IN RIVERS STATE
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2018, Vol 5, Issue 12
Abstract
Pregnancy, a physiological state in women of reproductive ages, is associated with an increased requirement of macro and micro nutrients. Iron is a vital micro nutrient for human population because it plays a key role in crucial biological processes. The aim of the study was to evaluate gestational changes in serum iron status and full blood count parameters among pregnant women in Rivers State. We determined serum ferritin, soluble transferrin receptor, serum iron, haemoglobin, haematocrit, mean cell volume, mean cell haemoglobin, mean cell corpuscular haemoglobin and red cell distribution width at 12, 20, and 30 weeks of gestation in a longitudinal study of 428 apparently healthy women who consist of 328 pregnant women and 100 non-pregnant who served as control in Rivers State of Nigeria. Full blood count parameters and their absolute values were measured using Sysmex 300 haematology autoanalyzer, while Ferritin and Iron were assayed using Enzyme Linked Immunosorbent Assay and Photometric methods. Data was analyzed using (Graph Pad Prism version 9.0, and NCSS version 9.0). Results obtained were expressed mean ± SD, median and 2.5-97.5 percentile. The prevalence of anaemia increased from 39.37%, to 89.33%, and 60.37%, at weeks 12, 20, and 30 respectively. The prevalence of iron deficiency anaemia defined as (sTfR>28nmol/l) was 17.99% at week 12, 17.68% at 20 and 35.98% at week 30. From the results, it has been shown that haemoglobin concentration, serum ferritin, soluble transferrin receptor are tools diagnosing iron deficiency. This study found a progressive increase in development of IDA, even with increase iron demand by fetus economic. We had provided data and evidence on changes in serum iron parameter in pregnancy, and further asserts that these parameters are key in the diagnosis of IDA in pregnancy.
Authors and Affiliations
Beauty Echonwere
Keywords
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