Clinical analysis of vitamin B12 deficiency mainly manifested by recurrent aphthous ulcers
Journal Title: 口腔疾病防治 - Year 2019, Vol 27, Issue 6
Abstract
Objective To analyze the clinical characteristics and treatment experience of Vitamin B12 (VB12) deficient patients with recurrent aphthous ulcers (RAU) to improve the clinical efficacy. Methods A retrospective analysis was performed on 15 cases of recurrent oral ulcers from January 2016 to September 2018. The causes were analyzed according to the patients’ clinical characteristics. Results In total, 15 patients with RAU had no remission after routine immunotherapy. Further clinical examination suggested that vitamin B12 levels were reduced. The erythrocyte mean corpuscular volume (MCV) was significantly increased, and the average number of red blood cells (RBC) and hemoglobin (Hb) levels were decreased. RAU disappeared after vitamin B12 supplementation. Routine blood work showed that the MCV returned to the normal range, which was statistically significant compared with the pretreatment MCV (P < 0.001). Vitamin B12 serum levels were significantly higher (P < 0.001) than those before treatment. Conclusion When the main manifestation of vitamin B12 deficiency is recurrent oral ulcer symptoms, dentists should examine the lesions carefully, inquire about the medical history in detail, and perform further serological tests when necessary to avoid the overuse of immunosuppressive drugs for treatment.
Authors and Affiliations
MENG Wenxia, FENG Lu, ZI Yunling, JIANG Liyi, LI Juxiong, ZHOU Zhen
Keywords
Related Articles
- EP ID EP623726
- DOI 10.12016/j.issn.2096-1456.2019.06.006
- Views 213
- Downloads 0
Research progress on the effect of adhesives residues on peri-implant diseases
Implant denture repair technology has become a superior repair method for dentition defects and missing teeth. With the rapid increase in the number of implants placed, the rate of implant failure has also increased. The...
CBCT study of three-dimensional morphological characteristics of upper airway in children and adolescents with skeletal class Ⅲ malocclusion
Objective To investigate the three-dimensional morphological characteristics of the upper airway in children and adolescents with skeletal class Ⅲ malformation and to explore the relationship between craniofacial structu...
Research progress into probiotics for the prevention of dental caries
Caries is an important public health problem that affect the quality of life of residents, and microorganisms is the most important factor in its incidence. Probiotics are types of microorganisms that are beneficial to t...
Establishment and analysis of a diagnosis and treatment database of dental and maxillofacial deformities
Objective To establish the first dento-maxillofacial deformity diagnosis and treatment database in China, provide reference for the clinical diagnosis and treatment of dento-maxillofacial deformity in China, and lay the...
Evolution of diagnostic criteria for Sjögren′s Syndrome
Sjögren′s syndrome lacks a single and objective diagnostic index, and its diagnosis often requires comprehensive analysis according to classification criteria. With increasing research and a deepening understanding of th...