Clinical and anamnestic characteristics of patients with acute pulmonary embolism
Journal Title: Серце і судини - Year 2019, Vol 0, Issue 1
Abstract
The aim — to analyze the features of the course and the main factors of development of pulmonary embolism (PE). Materials and methods. During the period from January 1, 2014 until July 1, 2018, 774 patients with acute pulmonary embolism aged from 21 to 88 years (average age 59.1 ± 13.9 years) were hospitalized at Kharkiv City Clinical Hospital №8. Intra‑hospital mortality was 4.9 % (38 patients). The criterion for inclusion in the study was acute pulmonary embolism, diagnosed by the results of multispiral computed tomographic angiography of the pulmonary arteries. All patients underwent general clinical examination, standard transthoracic echocardiography and ultrasound doppler examination of the lower extremity veins. The risk of venous thromboembolism and prognosis according to generally accepted scales were evaluated. Results and discussion. Most of the examined patients (83.8 %) had 2 and more risk factors for venous thromboembolism. Every fifth patient had an oncological disease, in particular, in 5.8 % of patients, it was first detected in a targeted search. According to the MCT‑angiography of the pulmonary artery and/or echocardiography, 72.8 % of patients had signs of dysfunction of the right ventricle. Persons with high and moderately high risk of early death (68.6 %) whose treatment regimens included thrombolytic therapy prevailed among the examined patients. In treatment of patients with low and moderate‑low risk, preference was given to new oral anticoagulants. Conclusions. In the period from 2014 to 2017 there was an increase in cases of acute pulmonary embolism verified by MCT‑angiography, which can be explained by an increase in the incidence of pulmonary embolism and its better detection. The disease was diagnosed with the same frequency in men and women, but women were almost 10 years older than men. Hospitalization of patients with pulmonary embolism in one hospital improves the quality of treatment, as evidenced by a decrease in mortality from 8.8 % in 2014 to 3.9 % in 2017.
Authors and Affiliations
V. I. Tseluyko, L. N. Yakovleva, S. N. Sukhova, O. V. Radchenko, N. V. Diolog
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