Clinical and Etiological Correlation of Seizures in Children from Birth to 18 Years of Age and Immediate Treatment Outcome
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Objective: To find out various causes and their clinical presentations of seizures at different pediatric age groups and to analyze whether clinical and etiological correlation which provides a means to identify seizures that have similar pathophysiological features and to determine the effective medications for specific seizure types and to known the incidence of seizures. Method: A prospective, descriptive, analytical, cohort study was conducted with a total of 150 patients of 18 years and younger who presented to the Pediatrics emergency department (PED) with the complaints of seizures formed the study population in RIMS Hospital, Kadapa. It was done during a period of August 2017 to January 2018. Results: Incidence of seizures among total pediatric admissions (TPA) was 3.3% while incidence of seizures among PED was 6.3%. Age wise distribution neonates 74 (49.3%) were more followed by infants and children 55 (36.7%) and adolescents 21 (14%). Gender wise distribution males (59%) were more prone to develop seizures than females (41%). In neonates HIE is major cause for seizures followed by febrile in infants and children and meningitis in adolescents. Most common type of seizures in neonates subtle followed by GTCS in infants & children and adolescents. Among 150 cases seizures are commonly treated with monotherapy i.e., phenobarbitone (pb) in neonates and pb/phenytoin/clobazam in infants & children and phenytoin /Valproic acid in adolescents. Conclusion: Our study concluded that clinical and etiological correlation of seizures helps for early initiation of appropriate treatment and observed immediate treatment outcomes and the incidence of seizures.
Authors and Affiliations
Dr. B. Vijai Anand Babu, Ch. Ascharya, J. Radhika, K. Sudha Rani, T. Chandana, Dr. P. Venkata ramana
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