Clinical and Etiological profile of Pediatric Bacterial Meningitis in a Tertiary care center
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Background: Bacterial meningitis constitutes one of the major causes of mortality and morbidity in Pediatric population. The prevalence of common pathogens has reduced in developing countries with implementation of successful vaccination against the pathogens. Laboratory surveillance of pathogens is crucial in formulating the empirical treatment guidelines in suspected cases of Bacterial meningitis. We conducted this study to determine the clinical profile and bacterial pathogen pattern in such cases in a tertiary center. Methods: A Single blinded Prospective study was conducted over one and half year duration and all suspected cases of acute bacterial meningitis were included in the study. Clinical features were recorded.CSF culture was done and biochemical analysis & cell counts of CSF were performed. Results were analyzed using SPSS 11.2 software version. Results: Among 150 children, 83 were male child, 67 were female children. Fever was the predominant complaint followed by altered sensorium, convulsion, and neck rigidity. Few cases were admitted with cranial nerve involvement, cerebellar signs, motor and sensory system involvement. Among the infants fever, refusal of feeds, bulging fontanel were common presentation. In our study, nearly 47 cases among 150 cases of suspected bacterial meningitis had positive growth in culture. Among culture positive cases Gram negative organisms were predominant than gram positive organisms. CONS was the single most common isolate in the study followed by others like GNB, Enterococci, Escherichia coli, S. aureus, and Klebsiella pneumonia. Conclusions: There is an overwhelming need to formulate locally suitable antibiotic policies in the management of cases of Pediatric bacterial meningitis. As the clinical manifestations are sometimes not clear, a high index of suspicion, laboratory evaluation of CSF and rational use of empirical antibiotics greatly reduce the morbidity and mortality of such cases.
Authors and Affiliations
Dr. L. Ilangumaran, Prof. Dr. D. Raj kumar, Dr. S. Murugesa Lakshmanan
Keywords
Related Articles
- EP ID EP554004
- DOI 10.9790/0853-1803023743.
- Views 60
- Downloads 0
Study on Vitamin D Deficiency and Its Associating Factors in Tertiary Care Center, Rajasthan
Introduction: Vitamin D deficiency does indeed constitute an epidemic in many populations across the world. It is essential to bone health and is a major regulator of calcium homeostasis. Research Question: prevalence an...
A New Light on Prosthodontics- Enhancing Treatment Modalities with Lasers
In this modern era, newer technologies and their applications improve the predictability and outcome of the conventional procedures to a great extent. Lasers are introduced into the field of dentistry in 1989, which is w...
MTA: A review of literature with clinical applications
Mineral trioxide aggregate (MTA) is a calcium silicate-based cement. It has remained a widereaching material in endodontics since its introduction in the 1990’s. Several studies have illustrated its use in various clinic...
Proptosis-An Otorhinological Perspective
.
Comparitive Study of Conventional And Topical Heparin Dressing in Lower Limb Diabetic Ulcers.
Background : lower limb diabetic ulcers are very difficult to treat due to the poor vascularity and brittle granulation tissue formed during the healing phase. So a novel method is needed apart from conventional dressing...