Clinical and histopathological analysis of skin biopsies at a tertiary care hospital
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 2
Abstract
Background: A large number of Skin conditions that might present to a dermatologist in daily practice ranging from acute to chronic. Majority of these can be quickly diagnosed. However some of these need time consuming investigation to confirm the clinical diagnosis. skin biopsy probably is the most commonly used ancillary aid to confirm clinical diagnosis. Prevalence of skin diseases varies from country to country and various regions within the same country. The skin lesions among the patients can be classified into various categories according to the morphology and can be confirmed by histology of skin biopsy. Objective: To analyse the clinico-histopathological pattern of various lesions of skin and to determine the agreement between clinical and histopathological diagnosis. Methods: A total of 60 cases of skin lesions were enrolled for the study. Clinical diagnosis was correlated by histopathological examination with H and E stain. Special stains were used as an when required. Results: Maximum number of cases showed infectious diseases consisting 23(38.33%) cases of all skin biopsies followed by non-infectious erythematous, papular and squamous diseases consisting of 15 (25%) cases, connective tissue diseases and biopsies having non-specific histology constituted 7 cases each (11.67%). Among non-infectious group, there were 4 (6.66%) cases of vesiculobullous and vesiculopustular diseases, and had 2 cases (3.33%) of genodermatoses. 1 case each from the group of folliculitis and cutaneous manifestation of gastrointestinal disease were seen. Conclusion: The overall accuracy of the clinical diagnosis depends upon the clinical and histopathological correlation and skin biopsy is clearly a worthwhile investigative procedure. Infectious diseases were the most common cutaneous diseases in our region
Authors and Affiliations
Rohit Gupta, Surendra Singh, Kishor Singh, Sanjay Kumar Kanodia
Keywords
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