Clinical and Immunologic Profile of Human Immunodeficiency Virus Infection In Children Diagnosed Using Provider-Initiated Testing And Counseling Strategy In Ido-Ekiti, Nigeria: A CrossSectional Study”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Background: Most children with HIV infection are not on antiretroviral drugs because their HIV status are not known. Provider-Initiated Testing and Counselling strategy aims at bridging this gap. The purpose of the present study was to determine the clinical and immunologic profile of HIV infection at presentation in the children detected to have HIV infection using PITC Strategy. Method:A hospital-based cross-sectional study. Consecutive new patients from birth to age of 15 years with unknown HIV sero-status who presented at the Paediatric Emergency Unit of FMC, Ido-Ekiti during the study period were offered HIV testing using PITC strategy.All the patients were clinically evaluated before the HIV test was done. Patients were examined for signs of HIV infectionbased on the revised WHO Paediatric Clinical Staging of HIV/AIDS Disease. Results: Common symptoms in children with HIV infection were fever, diarrhoea, fast breathing, cough, and poor weight gain/failure andcommon signs in patients with HIV infection were pallor, oral thrush, generalized lymphadenopathy, otorrhoea, hepatomegaly, splenomegaly and skin lesions. Only the presence of poor weight gain and generalised lymphadenopathy were independent predictors of HIV infection (p < 0.006).Twelve (50%) of the 24 patients with HIV infection presented in clinical stage 3 with another two (8.3%) in stage 4. Three (12.5%) of the patients were however in clinical stage 1. Twelve (50%) of the patients were severely immuno-suppressed and six (25.0%) were without significant immunodeficiency. Conclusion:HIV in children in Ido-Ekiti occurs and most cases presented with severe disease. Improved access to prevention services and early diagnosis are recommended.
Authors and Affiliations
OluwaseyiTosin Babatunde, Layi Solomon Babatunde
Keywords
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- EP ID EP369648
- DOI 10.9790/0853-1703106167.
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