Clinical and molecular characteristics of influenza outbreak in two military bases in Tumbes, Peru 2007
Journal Title: Revista Peruana de Medicina Experimental y Salud Publica - Year 2008, Vol 25, Issue 1
Abstract
[b][i]Objective. [/i][/b]To describe an Influenza outbreak in two military bases in Tumbes, department located in northern Peru. [b][i]Material and methods. [/i][/b]In patients within 5 days of symptoms the Ministry of Health case definition of Influenza-like illness was used. Nasal swabs were taken for Rapid Influenza Test (RIT) and throat swab for viral isolation, three cell lines (MDCK, VERO, LLCMK2) were used. For Influenza B genotypification we made a partial sequencing of hemaglutinine region of 898 pair bases, having 2007 vaccine strain B/Florida/4/2006 as a model. For Influenza A genotypification we analysed 958 pair bases, having 2007 vaccine strain A/Brisbane/10/2007 (H3N2) as a model. [b][i]Results.[/i][/b] We took 124 samples, 20 from military base (MB) # 1 and 104 from MB # 2. RIT promptly identified 41 positive cases: Flu B: 27, Flu A: 02, Flu: 12, with 62% of sensibility and specificity 100%. Finally, 66 cases were confirmed by virus isolation, 54 Flu B and 12 Flu A. Genotypification showed that isolates were genetically similar to Influenza B/Texas/4/2006 (n=34) and A/Texas/91/2007 (H3N2) (n=7). Most common symptoms found were fever, headache, malaise, cough, sore throat, myalgias and rinorrheae. Control strategies consisted to identify probable cases and to isolate them in a special room and to wear facemasks. [b][i]Conclusions.[/i][/b] We confirmed 66 cases by cellular culture. Isolates were genetically similar to influenza B/Texas/4/2006 and A/Texas/91/2007 (H3N2).
Authors and Affiliations
Tatiana Saldarriaga, V. Alberto Laguna-Torres , Juan Arrasco, Luis Guillén, Patricia Aguilar, Merly Sovero, Jane Ríos , María Gomero, Rommell González, Tadeusz Kochel
Keywords
Related Articles
- EP ID EP123755
- DOI -
- Views 94
- Downloads 0
Enfoque sociopolítico para el control de la tuberculosis en el Perú
La tuberculosis es una enfermedad social y es la responsable del mayor número de muertes en la historia de la humanidad. El bacilo de Koch encuentra en la pobreza, hacinamiento, exclusión social e inequidad los condicion...
Las unidades regionales de investigación en salud, Perú 2009.
Coverage of health insurance in relation with medical services use, living conditions and perceived health in Lima, Peru
[b]Objectives.[/b] Correlate affiliation to health insurance with the use of medical services, living conditions and perceived health of residents in 12 districts of Lima. [b]Material and methods[/b]. Descriptive cross-p...
[The Revista Peruana de Medicina Experimental y Salud Pública now indexed in MEDLINE/Index Medicus].
Recommendations for the control of tuberculosis transmission in hospitals
Nosocomial transmission of tuberculosis (TB) is a current problem in Peru, on the one hand because of the risk for health personal and for inpatients to acquire the infection, and on the other because of the increasing f...