Clinical and molecular features of one case of human infection with Anaplasma phagocytophilum from Podlaskie Province in eastern Poland
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2015, Vol 22, Issue 3
Abstract
The article focuses on the clinical and laboratory diagnosis of human granulocytic anaplasmosis (HGA) caused by [i]Anaplasma phagocytophilum[/i] infection in one of 28 patients (3.6%; n=1/28 tested samples) with early Lyme borreliosis. The clinical and laboratory results of a 42-year-old patient fulfilled criteria of confirm anaplasmosis and suggest an acute stage of illness. The described case provides strong presumptive evidence that infection in this patient was acquired with a pathogenic strain of [i]A. phagocytophilum[/i] through a tick bite. A positive DNA with PCR for A. phagocytophilum infection was sequenced and analyzed phylogenetically. Physicians should consider the possibility of anaplasmosis in patients with early Lyme borreliosis, and [i]A. phagocytophilum[/i] should be considered as a differential diagnosis in all patients from an endemic region of potential high risk factors for tick-borne diseases.
Authors and Affiliations
Renata Welc-Falęciak, Maciej Kowalec, Joanna Zajkowska, Sławomir Pancewicz, Edward Siński
Keywords
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