Clinical application of esmketamine hydrochloride combined with propofol in curettage of eyelid tumors in children
Journal Title: Eye Science (Yanke Xuebao) - Year 2022, Vol 37, Issue 9
Abstract
[Objective:] To investigate the anesthetic effect and to evaluate the efficacy and safety of combination application of esketamine and propofol in curettage of eyelid tumors of children. [Methods:] This study selected 70 children who underwent elective eyelid tumor curettage in Foshan Second People's Hospital from November 2020 to July 2021. They were randomly divided into group A and group B, with 35 cases in each group. Patients in Group A were anesthetized with sevoflurane combined with propofol. Patients in Group B were anesthetized with esketamine combined with propofol. The anesthetic induction time, operation time, recovery time and total recovery time of the two groups were recorded. The haemodynamics and respiratory frequency changes of patients were being monitored before anesthesia, 5 minutes after anesthesia, before the operation and after the operation. The scores of Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) pain, agitation and nausea and vomiting were recorded immediately after the patients awakened and were sent back to the ward. [Results:] There was no significant difference in anesthesia induction time between the two groups (P>0.05). There was also no significant difference in the haemodynamics and respiratory frequency changes during the anaesthetic process between the two groups (P>0.05). The recovery time and total recovery time in group B were significantly lower than those in group A (P<0.05). The scores of CHEOPS pain, agitation and nausea and vomiting in group B were significantly lower than those in group A immediately after the patients awakened and were sent back to the ward (P<0.05). Besides, the probability of nausea and vomiting after curettage of eyelid tumors was lower in group B than in group A (P<0.05). [Conclusion:] Combination application of esketamine and propofol in curettage of eyelid tumors of children can provide good anesthetic and analgesic effect and reduce the occurrence of restlessness, nausea and vomiting.
Authors and Affiliations
Shuxuan YANG, Xiaoli DU, Zhaoxia WU, Weijian CHEN, Xiaoxia LIANG, Xianjie WEN
Keywords
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- EP ID EP763736
- DOI 10.3978/j.issn.1000-4432.2022.04.02
- Views 12
- Downloads 0
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