Clinical behaviour of ocular surface squamous neoplasia (OSSN) in HIV positive patients
Journal Title: MRIMS Journal of Health Sciences - Year 2016, Vol 4, Issue 2
Abstract
Background: A lot of Ocular Surface Squamous Neoplasia(OSSN) may go unnoticed as they are asymptomatic and usually slow-growing. The prevalence of OSSN is more in tropical region and varies from 12 cases /million/ year in Uganda to 0.3 cases / million/ year in United States of America, possibly related to sunlight exposure. Objective: To study the clinical behaviour of Ocular Surface squamous neoplasia (OSSN) in HIV positive patients. Methods: This is a retrospective study done at the department of the oculoplastics and orbital diseases, Sarojini Devi Eye Hospital Hyderabad over a period of three years from February 2012 to January 2015. 26 cases of HIV positive patients with OSSN were included in the study and non HIV cases were excluded. Results: In our study of 26 cases 17 were males and 9 were females and average age of presentation was 34 years 10 to 15 years younger than non HIV cases. Histopathologically 18 cases were squamous cell carcinoma, 5 cases were carcinoma in situ and 3 cases were with moderate to severe dysplasia. Recurrence was seen in 8 cases (32.1%). Conclusion: OSSN presents at a younger age in HIV positive patients with aggressive behaviour clinically and histopathologically with more chances of recurrence.
Authors and Affiliations
P Padmavathi, D Padma Prabha, Mohd. Ather
Keywords
Related Articles
- EP ID EP422222
- DOI -
- Views 106
- Downloads 0
A study of Bcl-2 and p-53 immunostaining expressions in colonic carcinomas
Background: Colorectal cancer burden has been steadily rising in women. It was the fourth most common cancer in 1975 and has reached the second position by 1990, with about 49% increase in the number of cases globally ov...
Idiopathic Clubbing: A Case Report
Clubbing of the fingers and toes has been recognized as a clinical manifestation of intra thoracic disease from the earliest times. Hippocrates particularly described the condition as occurring with advanced phthisis and...
A study of effect of iron on hematological status in iron deficiency anemic children
Background: Iron Deficiency is the most widely prevalent nutritional disorder affecting the world population today. Anaemia has been described as a major health problem in the developing countries. Iron Deficiency Anaemi...
A study on stress levels among exam going post graduate medical students of a medical college in Telangana- A cross sectional study
Abstract: Background: Medicine is considered to be a stressful profession particularly during post graduate years. Stress is also linked to various diseases such as Hypertension and Diabetes etc. Hence, understanding st...
Evaluation of Intraocular Pressure (IOP) and Optic Disc in Primary Angle Closure Disease
Background: Primary Angle Closure Disease is a common cause of Blindness. Objectives: Our study was to evaluate the Intraocular Pressure and Optic Disc in the Primary Angle Closure Disease. Materials and Methods: This wa...